High-speed, image-based eye tracking with a scanning laser ophthalmoscope

被引：97
作者：
Sheehy, Christy K. [1 ]
Yang, Qiang [2 ]
Arathorn, David W. [2 ]
Tiruveedhula, Pavan [1 ]
de Boer, Johannes F. [3 ]
Roorda, Austin [1 ]
机构：
[1] Univ Calif Berkeley, Sch Optometry, Berkeley, CA 94720 USA
[2] Montana State Univ, Bozeman, MT 59717 USA
[3] Rotterdam Ophthalm Inst, Rotterdam, Netherlands
来源：
BIOMEDICAL OPTICS EXPRESS | 2012年 / 3卷 / 10期
基金：
美国国家卫生研究院;
关键词：
DESIGN;
D O I：
10.1364/BOE.3.002611
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
We demonstrate a high-speed, image-based tracking scanning laser ophthalmoscope (TSLO) that can provide high fidelity structural images, real-time eye tracking and targeted stimulus delivery. The system was designed for diffraction-limited performance over an 8 degrees field of view (FOV) and operates with a flexible field of view of 1 degrees-5.5 degrees. Stabilized videos of the retina were generated showing an amplitude of motion after stabilization of 0.2 arcmin or less across all frequencies. In addition, the imaging laser can be modulated to place a stimulus on a targeted retinal location. We show a stimulus placement accuracy with a standard deviation less than 1 arcmin. With a smaller field size of 2 degrees, individual cone photoreceptors were clearly visible at eccentricities outside of the fovea. (C) 2012 Optical Society of America
引用
收藏
页码：2611 / 2622
页数：12
相关论文
共 23 条
  • [1] American National Standards for Safe Use of Lasers, 2007, Z13612007 ANSI LAS I
  • [2] Retinally stabilized cone-targeted stimulus delivery
    Arathorn, David W.
    Yang, Qiang
    Vogel, Curtis R.
    Zhang, Yuhua
    Tiruveedhula, Pavan
    Roorda, Austin
    [J]. OPTICS EXPRESS, 2007, 15 (21) : 13731 - 13744
  • [3] ACCURATE 2-DIMENSIONAL EYE TRACKER USING FIRST AND FOURTH PURKINJE IMAGES
    CORNSWEET, TN
    CRANE, HD
    [J]. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA, 1973, 63 (08) : 921 - 928
  • [4] GENERATION-V DUAL-PURKINJE-IMAGE EYETRACKER
    CRANE, HD
    STEELE, CM
    [J]. APPLIED OPTICS, 1985, 24 (04): : 527 - 537
  • [5] Binocular coordination in microsaccades
    Engbert, R
    Kliegl, R
    [J]. MIND'S EYE: COGNITIVE AND APPLIED ASPECTS OF EYE MOVEMENT RESEARCH, 2003, : 103 - 117
  • [6] Garcia-Martin E, 2012, RETINA-J RET VIT DIS, V32, P1581, DOI 10.1097/IAE.0b013e318242b838
  • [7] First-order design of off-axis reflective ophthalmic adaptive optics systems using afocal telescopes
    Gomez-Vieyra, Armando
    Dubra, Alfredo
    Malacara-Hernandez, Daniel
    Williams, David R.
    [J]. OPTICS EXPRESS, 2009, 17 (21): : 18906 - 18919
  • [8] Efficient subpixel image registration algorithms
    Guizar-Sicairos, Manuel
    Thurman, Samuel T.
    Fienup, James R.
    [J]. OPTICS LETTERS, 2008, 33 (02) : 156 - 158
  • [9] Adaptive optics scanning laser ophthalmoscope for stabilized retinal imaging
    Hammer, DX
    Ferguson, RD
    Bigelow, CE
    Iftimia, NV
    Ustun, TE
    Burns, SA
    [J]. OPTICS EXPRESS, 2006, 14 (08): : 3354 - 3367
  • [10] The role of fixational eye movements in visual perception
    Martinez-Conde, S
    Macknik, SL
    Hubel, DH
    [J]. NATURE REVIEWS NEUROSCIENCE, 2004, 5 (03) : 229 - 240
123