Cesium trifluoroacetate or silver oxide mediated acyl migration for the construction of disaccharide building blocks

被引：16

作者：

Deng, SL ^{[1
]}

Chang, CWT ^{[1
]}

机构：

[1] Utah State Univ, Dept Chem & Biochem, Logan, UT 84322 USA

来源：

SYNLETT | 2006年 / 05期

关键词：

ABO blood group antigens; silver oxide; cesium trifluoroacetate; acyl migration; migration mechanisms;

D O I：

10.1055/s-2006-933105

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient method for the selective differentiation of the 2-OH and 3-OH of pyranosides, based on the CsO2CCF3- or Ag2O-mediated acyl migration, has been established. The 2-OH and 3-OH can be sequentially glycosylated by the desired carbohydrate generating disaccharides of biological interest. A mechanism involving either acid- or base-assisted acyl migration is proposed.

引用

页码：756 / 760

页数：5

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