Nosocomial outbreak of carbapenem-resistant Pseudomonas aeruginosa with a new blaIMP allele, blaIMP-7

被引：124

作者：

Gibb, AP

Tribuddharat, C

Moore, RA

Louie, TJ

Krulicki, W

Livermore, DM

Palepou, MFI

机构：

[1] Cent Publ Hlth Lab, Antibiot Resistance Monitoring & Reference Lab, London NW9 5HT, England

[2] Univ Calgary, Dept Microbiol & Infect Dis, Calgary, AB T2N 4N1, Canada

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 01期

关键词：

D O I：

10.1128/AAC.46.1.255-258.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Pseudomonas aeruginosa isolates from an outbreak in Canada were highly resistant to carbapenems and ceftazidime but not piperacillin. They produced a novel integron-associated metallo-beta -lactamase, designated IMP-7, with 91% identity to IMP-1. bla(IMP-7) was not detected with standard bla(IMP)-specific primers, owing to mismatches in the forward primer.

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页码：255 / 258

页数：4

相关论文

共 18 条

[1]

[Anonymous], 1999, M100S9 NAT COMM CLIN

[2]

Arakawa Y, 2000, J CLIN MICROBIOL, V38, P40

[3] In-vitro activity of cefepime and seven other antimicrobial agents against 1518 non-fermentative Gram-negative bacilli collected from 48 Canadian health care facilities [J].

Blondeau, JM ;

Laskowski, R ;

Borsos, S .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1999, 44 (04) :545-548

[4] IMP-4, a novel metallo-β-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998 [J].

Chu, YW ;

Afzal-Shah, M ;

Houang, ETS ;

Palepou, MFI ;

Lyon, DJ ;

Woodford, N ;

Livermore, DM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (03) :710-714

[5] Amino acid substitutions in a variant of IMP-1 metallo-β-lactamase [J].

Iyobe, S ;

Kusadokoro, H ;

Ozaki, J ;

Matsumura, N ;

Minami, S ;

Haruta, S ;

Sawai, T ;

O'Hara, K .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (08) :2023-2027

[6] PROPERTIES OF AN R-PLASMID IN PSEUDOMONAS-AERUGINOSA PRODUCING AMIKACIN (BB-K8), BUTIROSIN, KANAMYCIN, TOBRAMYCIN, AND SISOMICIN RESISTANCE [J].

JACOBY, GA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1974, 6 (06) :807-810

[7] Cloning and characterization of blaVIM, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate [J].

Lauretti, L ;

Riccio, ML ;

Mazzariol, A ;

Cornaglia, G ;

Amicosante, G ;

Fontana, R ;

Rossolini, GM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (07) :1584-1590

[8] PCR MAPPING OF INTEGRONS REVEALS SEVERAL NOVEL COMBINATIONS OF RESISTANCE GENES [J].

LEVESQUE, C ;

PICHE, L ;

LAROSE, C ;

ROY, PH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) :185-191

[9]

Livermore D.M., 1996, ANTIBIOTICS LAB MED, P502

[10] Carbapenemases: a problem in waiting? [J].

Livermore, DM ;

Woodford, N .

CURRENT OPINION IN MICROBIOLOGY, 2000, 3 (05) :489-495