Tissue Engineering for Intervertebral Disk Degeneration

被引：21
作者：
Leung, Victor Y. L. [1 ]
Tam, Vivian [1 ]
Chan, Danny [2 ]
Chan, Barbara P. [3 ]
Cheung, Kenneth M. C. [4 ]
机构：
[1] Univ Hong Kong, Dept Orthopaed & Traumatol, Pokfulam, Hong Kong, Peoples R China
[2] Univ Hong Kong, Dept Biochem, Pokfulam, Hong Kong, Peoples R China
[3] Univ Hong Kong, Dept Mech Engn, Tissue Engn Lab, Pokfulam, Hong Kong, Peoples R China
[4] Univ Hong Kong, Dept Orthopaed & Traumatol, Div Spine Surg, Li Ka Shing Fac Med, Pokfulam, Hong Kong, Peoples R China
来源：
ORTHOPEDIC CLINICS OF NORTH AMERICA | 2011年 / 42卷 / 04期
关键词：
Intervertebral disk; Degeneration; Tissue engineering;
D O I：
10.1016/j.ocl.2011.07.003
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Many challenges confront intervertebral disk engineering owing to complexity and the presence of extraordinary stresses. Rebuilding a disk of native function could be useful for removal of the symptoms and correction of altered spine kinematics. Improvement in understanding of disk properties and techniques for disk engineering brings promise to the fabrication of a functional motion segment for the treatment of disk degeneration. Increasing sophistication of techniques available in biomedical sciences will bring its application into clinics. This review provides an account of current progress and challenges of intervertebral disk bioengineering and discusses means to move forward and toward bedside translation.
引用
收藏
页码：575 / +
页数：10
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