Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer

被引:6
|
作者
Stubbe, JoAnne [1 ]
Seyedsayamdost, Mohammad R. [2 ]
机构
[1] MIT, Dept Chem, Cambridge, MA 02139 USA
[2] Princeton Univ, Dept Chem, Frick Lab, Princeton, NJ 08544 USA
基金
美国国家卫生研究院;
关键词
Number:; GM081393; Acronym:; NIH; Sponsor: National Institutes of Health; R01GM029595; NIGMS; Sponsor: National Institute of General Medical Sciences; -; Sponsor: Camille and Henry Dreyfus Foundation;
D O I
10.1021/acs.biochem.8b01238
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:435 / 437
页数:3
相关论文
共 50 条
  • [31] Cysteinyl and substrate radical formation in active site mutant E441Q of Escherichia coli class I ribonucleotide reductase
    Persson, AL
    Sahlin, M
    Sjöberg, BM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (47) : 31016 - 31020
  • [32] A Proton Wire Mediates Proton Coupled Electron Transfer from Hydroxyurea and Other Hydroxamic Acids to Tyrosyl Radical in Class Ia Ribonucleotide Reductase
    Offenbacher, Adam R.
    Barry, Bridgette A.
    JOURNAL OF PHYSICAL CHEMISTRY B, 2020, 124 (02): : 345 - 354
  • [33] Nickel-Sulfonate Mode of Substrate Binding for Forward and Reverse Reactions of Methyl-SCoM Reductase Suggest a Radical Mechanism Involving Long-Range Electron Transfer
    Patwardhan, Anjali
    Sarangi, Ritimukta
    Ginovska, Bojana
    Raugei, Simone
    Ragsdale, Stephen W.
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 143 (14) : 5481 - 5496
  • [34] Gating of Substrate Access and Long-Range Proton Transfer in Escherichia coli Nitrate Reductase A: The Essential Role of a Remote Glutamate Residue
    Al-Attar, Sinan
    Rendon, Julia
    Sidore, Marlon
    Duneau, Jean-Pierre
    Seduk, Farida
    Biaso, Frederic
    Grimaldi, Stephane
    Guigliarelli, Bruno
    Magalon, Axel
    ACS CATALYSIS, 2021, 11 (23) : 14303 - 14318
  • [35] 2,3-difluorotyrosine at position 356 of ribonucleotide reductase R2: A probe of long-range proton-coupled electron transfer
    Yee, CS
    Chang, MCY
    Ge, J
    Nocera, DG
    Stubbe, J
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (35) : 10506 - 10507
  • [37] Intramolecular photoinduced electron transfer to anthraquinones linked to duplex DNA: The effect of gaps and traps on long-range radical cation migration
    Gasper, SM
    Schuster, GB
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (52) : 12762 - 12771
  • [39] A new mechanism-based radical intermediate in a mutant R1 protein affecting the catalytically essential Glu(441) in Escherichia coli ribonucleotide reductase
    Persson, AL
    Eriksson, M
    Katterle, B
    Potsch, S
    Sahlin, M
    Sjoberg, BM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (50) : 31533 - 31541
  • [40] Long-Range Chirality Transfer in Free Radical Polymerization of Bulky Vinyl Monomers Containing Laterally Attached p-Terphenyl Groups
    Cui, Jiaxi
    Lu, Xiaocun
    Liu, Anhua
    Wan, Xinhua
    Zhou, Qifeng
    MACROMOLECULES, 2009, 42 (20) : 7678 - 7688