Norcyperone, a Novel Skeleton Norsesquiterpene from Cyperus rotundus L.

被引：35

作者：

Xu, Yan ^{[1
,2
]}

Zhang, Hong-Wu ^{[1
,2
]}

Yu, Chang-Yuan ^{[3
]}

Lu, Yang ^{[2
,4
]}

Chang, Ying ^{[2
,4
]}

Zou, Zhong-Mei ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci, Inst Med Plant Dev, Beijing 100193, Peoples R China

[2] Peking Union Med Coll, Beijing 100193, Peoples R China

[3] Beijing Univ Chem Technol, Coll Life Sci & Technol, Beijing 100029, Peoples R China

[4] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

来源：

MOLECULES | 2008年 / 13卷 / 10期

基金：

中国国家自然科学基金;

关键词：

Cyperus rotundus L; norsesquiterpene; norcyperone; bicyclo[5.3.1]undecane-3-one;

D O I：

10.3390/molecules13102474

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel norsesquiterpene, named norcyperone 1), and three known compounds: (-)-clovane-2,9-diol 2), rosenonolactone 3), and 5 alpha,8 alpha-epidioxy-20S, 22E, 24R)-ergosta-6,22- dien-3 beta-ol 4) were isolated from the rhizomes of Cyperus rotundus L. The structure of 1 was elucidated as 8,11,11-trimethylbicyclo[5.3.1] undecane-5 alpha, 8 alpha-epoxy-3-one on the basis of extensive spectroscopic analyses, including 1D- and 2D-NMR, MS experiments, and single-crystal X-ray diffraction. This is the first report of a 8,11,11-trimethyl- bicyclo[5.3.1] undecane-3-one type norsesquiterpene with a tetrahydrofuran ring at C-5 and C-8

引用

页码：2474 / 2481

页数：8

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