Gene-environment contributions to energy and macronutrient intakes in 9-year-old children: Results from the Quebec Newborn Twin Study

被引:9
作者
Dubois, Lise [1 ,2 ]
Diasparra, Maikol [1 ]
Bedard, Brigitte [1 ]
Kaprio, Jaakko [3 ,4 ,5 ]
Fontaine-Bisson, Benedicte [6 ]
Perusse, Daniel [7 ]
Tremblay, Richard [8 ,9 ]
Boivin, Michel [10 ]
机构
[1] Univ Ottawa, Inst Populat Hlth, Ottawa, ON K1N 6N5, Canada
[2] Univ Ottawa, Dept Epidemiol & Community Med, Ottawa, ON K1H 8M5, Canada
[3] Univ Helsinki, Dept Publ Hlth, Hjelt Inst, FIN-00014 Helsinki, Finland
[4] Natl Inst Hlth & Welf, Dept Mental Hlth & Subst Abuse Serv, Helsinki 00300, Finland
[5] Univ Helsinki, Inst Mol Med FIMM, FIN-00014 Helsinki, Finland
[6] Univ Ottawa, Nutr Sci Program, Ottawa, ON K1N 6N1, Canada
[7] Univ Montreal, Dept Anthropol, Montreal, PQ H3C 3J7, Canada
[8] Univ Montreal, Res Unit Childrens Psychosocial Maladjustment GRI, Montreal, PQ H3C 3J7, Canada
[9] Univ Coll Dublin, Sch Publ Hlth Physiotherapy & Populat Sci, Dublin 4, Ireland
[10] Univ Laval, Ecole Psychol, Quebec City, PQ, Canada
基金
加拿大健康研究院;
关键词
Energy intake; Macronutrients; Children; Twins; Heritability; Environment; FREE-LIVING HUMANS; FOOD-INTAKE; DIETARY-INTAKE; OBESITY; HERITABILITY; PREFERENCES; PATTERNS; FAT; CD36; OVERWEIGHT;
D O I
10.1016/j.physbeh.2013.05.039
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Background: Few twin studies have examined nutrition-related phenotypes among children, and none has investigated energy and macronutrient intakes. Objective: The objective was to quantify genetic and environmental influences on variations in energy and macronutrient intakes among children aged 9 years. Design: We conducted a nutrition study among children participating in the Quebec Newborn Twin Study, a population-based birth cohort of twins. We derived dietary data from two multiple-pass 24-hour dietary recalls with a parent and his or her child. The analysis employed a classic twin study design and used data from 379 twin pairs. Results: Univariate analyses indicate that heritability for mean daily energy (kcal) and macronutrient (g) intakes was moderate, ranging from 0.34(95% CI: 0.22, 0.46) to 0.42 (0.31, 0.53). Genetic effects also accounted for 0.28 (0.16, 0.40) of the variance-in percent of energy from lipids, while only environmental (shared and unique) effects accounted for the variance in percent of energy from proteins and carbohydrates. The shared environment did not contribute to variations in daily intakes for most of the nutritional variables under study. Multivariate analyses suggest the presence of macronutrient-specific genetic influences for lipids and carbohydrates, estimated at 0.12 (0.04, 0.19) and 0.20 (0.11, 029) respectively. Conclusions: The unique environment (i.e., not shared by family members) has the largest influence on variances in daily energy and macronutrient intakes in 9-year-old children. This finding underscores the need to take obesogenic environments into account when planning dietary interventions for younger populations. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:30 / 37
页数:8
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