Concept of the Flemish human biomonitoring programme

被引：87

作者：

Schoeters, Greet ^{[1
,2
,11
]}

Den Hond, Elly ^{[1
,11
]}

Colles, Ann ^{[1
,11
]}

Loots, Ilse ^{[11
]}

Morrens, Bert ^{[3
,11
]}

Keune, Hans ^{[3
,11
]}

Bruckers, Liesbeth ^{[4
,11
]}

Nawrot, Tim ^{[5
,6
,11
]}

Sioen, Isabelle ^{[7
,10
,11
]}

De Coster, Sam ^{[8
,11
]}

Van Larebeke, Nicolas ^{[8
,11
]}

Nelen, Vera ^{[9
,11
]}

Van de Mieroop, Els ^{[9
,11
]}

Vrijens, Jan ^{[10
,11
]}

Croes, Kim ^{[10
,11
]}

Goeyens, Karen ^{[10
,11
]}

Baeyens, Willy ^{[10
,11
]}

机构：

[1] Flemish Inst Technol Res VITO, Mol, Belgium

[2] Univ Antwerp, Dept Biomed Sci, B-2020 Antwerp, Belgium

[3] Univ Antwerp, Fac Polit & Social Sci, B-2020 Antwerp, Belgium

[4] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Hasselt, Belgium

[5] KULeuven, Dept Publ Hlth, Louvain, Belgium

[6] Hasselt Univ, Ctr Environm Sci, Diepenbeek, Belgium

[7] Univ Ghent, Dept Publ Hlth, B-9000 Ghent, Belgium

[8] Univ Ghent, Dept Radiotherapy & Nucl Med, B-9000 Ghent, Belgium

[9] Prov Inst Hyg PIH, Antwerp, Belgium

[10] Vrije Univ Brussel, Brussels, Belgium

[11] FWD Res Fdn Flanders, Brussels, Belgium

来源：

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH | 2012年 / 215卷 / 02期

基金：

比利时弗兰德研究基金会;

关键词：

Human biomonitoring; General population; Hot spots; Reference values; Stakeholder dialogue; Participatory process; PARTICIPATORY RESEARCH; INTERNAL EXPOSURE; HUMAN SERUM; HEALTH; POLLUTANTS; BLOOD; ORGANOCHLORINE; ENVIRONMENT; CARCINOGENS; EXTRACTION;

D O I：

10.1016/j.ijheh.2011.11.006

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Since 2002 a human biomonitoring network has been established in Flanders (Belgium) as part of a programme on environmental health surveillance. The human biomonitoring network should support environmental health policy by identifying priorities for further action. The first cycle of the programme (2002-2006) confirmed the hypotheses that living in areas with different environmental pressure is reflected in different loads of environmental chemicals in the residents. In the second cycle of the programme (2007-2011) the number of environmental chemicals for which human biomonitoring data were obtained was expanded substantially. The goal of the Flemish programme is to use and translate the scientific results into policy actions. Its further orientation in the second cycle to human biomonitoring in hot spots and sensitive age groups or susceptible persons with underlying complications (e.g. persons with diabetes) are linked to these goals. Interaction with stakeholders is embedded in the programme emphasizing transparency of the choices that are made and direct communication. The Flemish human biomonitoring programme is organized centrally with major involvement of research partners from different disciplines which allows engrafting environmental health research on the programme. One of the major focuses is the question whether combinations of pollutants in the general population are associated with biological effects. The objective of this paper is to review and discuss the options that were taken in the human biomonitoring programme in order to achieve its goals. (C) 2011 Elsevier GmbH. All rights reserved.

引用

页码：102 / 108

页数：7

共 32 条

[1] Exposure and effect monitoring: a critical appraisal of their practical application [J].

Aitio, A ;

Kallio, A .

TOXICOLOGY LETTERS, 1999, 108 (2-3) :137-147

[2] Application of non-invasive biomarkers in a birth cohort follow-up in relation to respiratory health outcome [J].

Bloemen, Karolien ;

Koppen, Gudrun ;

Govarts, Eva ;

Colles, Ann ;

Van Den Heuvel, Rosette ;

Nelen, Vera ;

Witters, Erwin ;

Desager, Kristine ;

Schoeters, Greet .

BIOMARKERS, 2010, 15 (07) :583-593

[3] Simplified method for determination of organochlorine pollutants in human serum by solid-phase disk extraction and gas chromatography [J].

Covaci, A ;

Schepens, P .

CHEMOSPHERE, 2001, 43 (4-7) :439-447

[4] Optimization of the determination of polybrominated diphenyl ethers in human serum using solid-phase extraction and gas chromatography-electron capture negative ionization mass spectrometry [J].

Covaci, A ;

Voorspoels, S .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2005, 827 (02) :216-223

[5] Analysis of PCDD/Fs and dioxin-like PCBs in atmospheric deposition samples from the Flemish measurement network: Optimization and validation of a new CALUX bioassay method [J].

Croes, K. ;

Van Langenhove, K. ;

Elskens, M. ;

Desmedt, M. ;

Roekens, E. ;

Kotz, A. ;

Denison, M. S. ;

Baeyens, W. .

CHEMOSPHERE, 2011, 82 (05) :718-724

[6] Hormone levels and sexual development in Flemish adolescents residing in areas differing in pollution pressure [J].

Croes, K. ;

Baeyens, W. ;

Bruckers, L. ;

Den Hond, E. ;

Koppen, G. ;

Nelen, V. ;

Van de Mieroop, E. ;

Keune, H. ;

Dhooge, W. ;

Schoeters, G. ;

Van Larebeke, N. .

INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2009, 212 (06) :612-625

[7] Internal exposure to pollutants and sexual maturation in Flemish adolescents [J].

Den Hond, Elly ;

Dhooge, Willem ;

Bruckers, Liesbeth ;

Schoeters, Greet ;

Nelen, Vera ;

van de Mieroop, Els ;

Koppen, Gudrun ;

Bilau, Maaike ;

Schroijen, Carmen ;

Keune, Hans ;

Baeyens, Willy ;

van Larebeke, Nicolas .

JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 2011, 21 (03) :224-233

[8] Determinants of polychlorinated aromatic hydrocarbons in serum in three age classes-Methodological implications for human biomonitoring [J].

Den Hond, Elly ;

Govarts, Eva ;

Bruckers, Liesbeth ;

Schoeters, Greet .

ENVIRONMENTAL RESEARCH, 2009, 109 (04) :495-502

[9] Internal exposure to pollutants and sex hormone levels in Flemish male adolescents in a cross-sectional study: associations and dose-response relationships [J].

Dhooge, Willem ;

Den Hond, Elly ;

Koppen, Gudrun ;

Bruckers, Liesbeth ;

Nelen, Vera ;

van de Mieroop, Els ;

Bilau, Maaike ;

Croes, Kim ;

Baeyens, Willy ;

Schoeters, Greet ;

van Larebeke, Nicolas .

JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 2011, 21 (01) :106-113

[10] Mercury speciation in hair by headspace injection-gas chromatography-atomic fluorescence spectrometry (methylmercury) and combustion-atomic absorption spectrometry (total Hg) [J].

Gao, Y. ;

De Galan, S. ;

De Brauwere, A. ;

Baeyens, W. ;

Leermakers, M. .

TALANTA, 2010, 82 (05) :1919-1923

← 1 2 3 4 →