A dual-response near-infrared fluorescent probe for rapid detecting thiophenol and its application in water samples and bio-imaging

被引：30

作者：

Li, Yaqian ^{[1
]}

Su, Wei ^{[1
]}

Zhou, Zile ^{[1
]}

Huang, Zhen ^{[1
]}

Wu, Cuiyan ^{[1
]}

Yin, Peng ^{[1
]}

Li, Haitao ^{[1
]}

Zhang, Youyu ^{[1
]}

机构：

[1] Hunan Normal Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Chem Biol & Tradit Chinese Med Res, Changsha 410081, Hunan, Peoples R China

来源：

TALANTA | 2019年 / 199卷

基金：

中国国家自然科学基金;

关键词：

Near-infrared fluorescent probe; Thiophenol; Rapid detection; Water samples; Living cells; HIGHLY SELECTIVE DETECTION; SENSITIVE DETECTION; ENVIRONMENTAL-SAMPLES; RECENT PROGRESS; LIVING CELLS; AMINO-ACIDS; CYSTEINE; GLUTATHIONE; COMPLEX; SYSTEM;

D O I：

10.1016/j.talanta.2019.02.022

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Thiophenol is widely known as a highly toxic substance that can cause serious harm to the environment and health. Rapid and non-destructive detection of thiophenol is of great significance for environmental management. In this work, we designed and synthesized a near-infrared (NIR) fluorescent probe, (E)-4-(2-(4-(dicyanomethylene)-4H-chromen-2-yl)vinyl)-2-formylphenyl-2,4-dinitrobenzenesulfonate (DCM-CHO-D), that can respond to thiophenol rapidly (less than 3 min) based on intramolecular charge transfer (ICT) mechanism. DCM-CHO-D has high selectivity and sensitivity to the detection of thiophenol. And there is a linear relationship between the fluorescence intensity of DCM-CHO-D and thiophenol concentration in the range of 0-10 mu M, the limit of detection (LOD) is as low as 0.22 mu M. What's more, DCM-CHO-D can not only be used as an ideal colorimetric tool for detecting thiophenol in water samples, but also image thiophenol in living cells, indicating its potential utility for thiophenol sensing in environmental and biological samples.

引用

页码：355 / 360

页数：6

共 45 条

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