Psychosexual distress following routine primary human papillomavirus testing: a longitudinal evaluation within the English Cervical Screening Programme

被引:11
作者
Bennett, K. F. [1 ]
Waller, J. [1 ,2 ]
McBride, E. [1 ]
Forster, A. S. [1 ]
Di Gessa, G. [3 ]
Kitchener, H. [4 ]
Marlow, L. A., V [1 ,2 ]
机构
[1] UCL, Dept Behav Sci & Hlth, Canc Commun & Screening Grp, London, England
[2] Kings Coll London, Sch Canc & Pharmaceut Sci, Canc Prevent Grp, London, England
[3] UCL, Dept Epidemiol & Publ Hlth, London, England
[4] Univ Manchester, Womens Canc Ctr, Inst Canc Sci, Manchester, Lancs, England
基金
英国医学研究理事会;
关键词
Cervical screening; human papillomavirus; psychosexual distress; PSYCHOLOGICAL IMPACT; PSYCHOSOCIAL IMPACT; WOMEN;
D O I
10.1111/1471-0528.16460
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective To assess psychosexual distress over a 12-month period among women receiving different human papillomavirus (HPV) and cytology results in the context of the English HPV primary screening pilot. Design Longitudinal, between-group study. Setting Five sites in England where primary HPV testing was piloted. Population Women aged 24-65 years (n = 1133) who had taken part in the NHS Cervical Screening Programme. Methods Women were sent a postal questionnaire soon after receiving their screening results (baseline) and 6 and 12 months later. Data were analysed using linear regression models to compare psychosexual outcomes between groups receiving six possible combinations of HPV and cytology screening results, including a control group with normal cytology and no HPV test. Main outcome measures Psychosexual distress, assessed using six items from the Psychosocial Effects of Abnormal Pap Smears Questionnaire (PEAPS-Q). Results At all time points, there was an association between screening result group and psychosexual distress (allP < 0.001). At baseline, mean psychosexual distress score (possible range: 1-5) was significantly higher among women with HPV and normal cytology (B = 1.15, 95% CI 0.96-1.34), HPV and abnormal cytology (B = 1.02, 95% CI: 0.78-1.27) and persistent HPV (B = 0.90, 95% CI 0.70-1.10) compared with the control group (allP < 0.001). At the 6 and 12 month follow ups the pattern of results were similar, but coefficients were smaller. Conclusions Our findings suggest receiving an HPV-positive result can cause psychosexual distress, particularly in the short-term. Developing interventions to minimise the psychosexual burden of testing HPV-positive will be essential to avoid unnecessary harm to the millions of women taking part in cervical screening. Tweetable abstract Receiving an HPV-positive result following primary HPV testing can cause psychosexual distress, particularly in the short-term.
引用
收藏
页码:745 / 754
页数:10
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