Modern outcomes of oesophageal atresia: Single centre experience over the last twenty years

被引:89
作者
Koivusalo, Antti I. [1 ]
Pakarinen, Mikko P. [1 ]
Rintala, Risto J. [1 ]
机构
[1] Childrens Hosp Univ Helsinki, Sect Paediat Surg, Helsinki, Finland
关键词
Oesophageal atresia; Trachea-oesophageal fistula; Oesophageal replacement; TRACHEOESOPHAGEAL FISTULA; OESOPHAGEAL ATRESIA; FOLLOW-UP; REPAIR; STRICTURES; MORBIDITY; CHILDREN; SURGERY; INFANTS; REFLUX;
D O I
10.1016/j.jpedsurg.2012.11.007
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Aim of the Study: The aim of this study was assessment of the contemporary outcomes of oesophageal atresia (OA) in a national paediatric surgical centre. Patients and Methods: A review of the hospital records of all patients who underwent repair of oesophageal atresia (OA) in our institute between 1991 and 2011 was performed. Results: The study included 130 consecutive infants with OA: types A (n=4, 3%), B (n=2, 2%), C (n=110, 85%), D (n=5, 4%), and E (n=9, 7%). Median follow-up was 8.8 (range 0.1-21) years. Twenty-nine (22%) infants had cardiac and 76 (58%) other anomalies, and seventeen (13%) had a long-gap OA. The final repair was primary (n = 113, 87%) or delayed (n=3) end-to-end anastomosis, oesophageal replacement (n=8) (6%) with gastric tube (n=4) or with jejunum interposition (n=4), and closure of the trachea-oesophageal fistula (Type E, n=9). Oesophageal continuity was achieved in all patients. Overall mortality was 3/130 (2%) and caused by gastric perforation (n=1), prolonged apnoeic spell (n = 1), and food asphyxiation (n=1). Oral feeds were achieved in 121 (94%) children. Eight (6%) children remain dependent on feeding ostomy. Long-gap OA was a major predictor of post-repair complications. Conclusion: The modern outcome for infants with OA is characterized by an extremely low hospital mortality and satisfactory oesophageal function, enabling full oral feeds in the vast majority of children. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:297 / 303
页数:7
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