Monoterpene glycosides from Indigofera hetrantha

被引:3
|
作者
Mehmood, Sajid [1 ]
Aziz-Ur-Rahman [2 ]
Ahmad, Zaheer [3 ]
Afza, Nighat [1 ]
Malik, Abdul [2 ]
Ahmad, Habib [4 ]
Choudhary, Muhammad Iqbal [2 ]
机构
[1] PCSIR Labs Karachi Complex, Pharmaceut Res Ctr, Karachi 75280, Pakistan
[2] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem Sci, Karachi 75270, Pakistan
[3] Univ Karachi, Dept Chem, Karachi 75270, Pakistan
[4] Govt Postgrad Jahanzeb Coll, Dept Bot, Saidu Sharif, Pakistan
关键词
Indigofera hetrantha; Leguminosae; Monoterpene glycosides; Lipoxygenase inhibition;
D O I
10.1080/14786410801980097
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Monoterpene glycosides have been isolated from the ethyl acetate soluble fraction of Indigofera hetrantha and their structures assigned to be 3,7-dimethyl-2(E),6-octadien-5-one-1-O-beta-D-6-O-acetylglucopyranoside (1) and 3,7-dimethyl-2(E), 6-octadien-5-one-1-O-[-beta-D-6"-O-acetylglucopyra-nosyl (1" -> 6')-beta-D-glucopyranoside] (2), on the basis of spectroscopic analysis including 1D and 2D NMR techniques. Compounds 1 and 2 displayed moderate inhibitory potential against the enzyme lipoxygenase.
引用
收藏
页码:1189 / 1195
页数:7
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