Formation of DNA adducts using nickel(II) complexes of redox-active ligands: a comparison of salen and peptide complexes

被引：92
|
作者：
Muller, JG
Kayser, LA
Paikoff, SJ
Duarte, V
Tang, N
Perez, RJ
Rokita, SE
Burrows, CJ [1 ]
机构：
[1] Univ Utah, Dept Chem, Salt Lake City, UT 84112 USA
[2] SUNY Stony Brook, Dept Chem, Stony Brook, NY 11794 USA
[3] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20792 USA
来源：
COORDINATION CHEMISTRY REVIEWS | 1999年 / 185-6卷
关键词：
nickel; salen; peptides; DNA; oxidation;
D O I：
10.1016/S0010-8545(99)00043-0
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A series of water-soluble Ni(salen) complexes have been synthesized and studied under oxidative conditions with DNA. Experiments involving gel electrophoretic analysis, substituent effect studies, and mass spectral characterization point to the formation of covalent adducts of the salen ligand with guanine nucleobases. The mechanism of this novel reactivity of transition metal complexes with nucleic acids is discussed in comparison with nickel(II) complexes of peptides and other ligands. (C) 1999 Elsevier Science S.A. All rights reserved.
引用
收藏
页码：761 / 774
页数：14
相关论文
共 50 条
  • [41] Sn and Ge Complexes with Redox-Active Ligands as Efficient Interfacial Membrane-like Buffer Layers for p-i-n Perovskite Solar Cells
    Akbulatov, Azat F.
    Akyeva, Anna Y.
    Shangin, Pavel G.
    Emelianov, Nikita A.
    Krylova, Irina V.
    Markova, Mariya O.
    Labutskaya, Liliya D.
    Mumyatov, Alexander V.
    Tuzharov, Egor I.
    Bunin, Dmitry A.
    Frolova, Lyubov A.
    Egorov, Mikhail P.
    Syroeshkin, Mikhail A.
    Troshin, Pavel A.
    MEMBRANES, 2023, 13 (04)
  • [42] Mononuclear and Dinuclear Copper Complexes of Tridentate Redox-active Ligands with Tunable H-bonding Donors: Structure, Spectroscopy and H+/e- Reactivity
    Wu, Tong
    Musgrove, Justin
    Siegler, Maxime A.
    Garcia-Bosch, Isaac
    CHEMISTRY-AN ASIAN JOURNAL, 2021, 16 (12) : 1608 - 1618
  • [43] Alkene Hydrosilylation Using Tertiary Silanes with α-Diimine Nickel Catalysts. Redox-Active Ligands Promote a Distinct Mechanistic Pathway from Platinum Catalysts
    Pappas, Iraklis
    Treacy, Sean
    Chirik, Paul J.
    ACS CATALYSIS, 2016, 6 (07): : 4105 - 4109
  • [44] Synthesis, DNA/BSA binding studies and in vitro biological assay of nickel(II) complexes incorporating tridentate aroylhydrazone and triphenylphosphine ligands
    Li, Yun
    Li, Yueqin
    Wang, Nana
    Lin, Dong
    Liu, Xiaohui
    Yang, Yong
    Gao, Qinwei
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 38 (17) : 4977 - 4996
  • [45] Some new Schiff base ligands giving a NNOS coordination sphere and their nickel(II) complexes: Synthesis, characterization and complex formation
    Asadi, Mozaffar
    Mohammadi, Khosro
    Esmaielzadeh, Sheida
    Etemadi, Bijan
    Fun, Hoon Kun
    POLYHEDRON, 2009, 28 (08) : 1409 - 1418
  • [46] Formation of Oligo-Nuclear Carboxylate Nickel(II) Complexes with Nitrogen-Containing Ligands. Quantum-Chemical Simulation
    N. S. Panina
    A. A. Nikiforov
    D. O. Blinou
    E. N. Dubrov
    A. I. Ponyaev
    A. V. Eremin
    A. N. Belyaev
    Russian Journal of General Chemistry, 2019, 89 : 2264 - 2272
  • [47] Formation of Oligo-Nuclear Carboxylate Nickel(II) Complexes with Nitrogen-Containing Ligands. Quantum-Chemical Simulation
    Panina, N. S.
    Nikiforov, A. A.
    Blinou, D. O.
    Dubrov, E. N.
    Ponyaev, A. I.
    Eremin, A. V.
    Belyaev, A. N.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2019, 89 (11) : 2264 - 2272
  • [48] Nickel(II) complexes bearing a pincer ligand containing thioamide units: Comparison between SNS- and SCS-pincer ligands
    Koizumi, Take-aki
    Teratani, Takuya
    Okamoto, Ken
    Yamamoto, Takakazu
    Shimoi, Yukihiro
    Kanbara, Takaki
    INORGANICA CHIMICA ACTA, 2010, 363 (11) : 2474 - 2480
  • [49] Highly active neutral nickel(II) complexes bearing P,N-chelate ligands: Synthesis, characterization and their application to addition polymerization of norbornene
    Wang, HY
    Jin, GX
    EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2005, (09) : 1665 - 1670
  • [50] New C2-symmetric optically active salen ligands and their cobalt(II) complexes. Hydridoborate reduction of prochiral C=O and C=C bonds
    L. O. Nindakova
    F. M. Lebed’
    A. Yu. Zamazei
    B. A. Shainyan
    Russian Journal of Organic Chemistry, 2007, 43 : 1322 - 1329
12345