Molecular Logic Gates for DNA Analysis: Detection of Rifampin Resistance in M. tuberculosis DNA

被引:41
作者
Cornett, Evan M. [1 ,2 ]
Campbell, Eleanor A. [1 ]
Gulenay, George [2 ]
Peterson, Evan [3 ]
Bhaskar, Neha [3 ]
Kolpashchikov, Dmitry M. [1 ,2 ]
机构
[1] Univ Cent Florida, Dept Chem, Orlando, FL 32816 USA
[2] Univ Cent Florida, Burnett Sch Biomed Sci, Orlando, FL 32816 USA
[3] Lake Highland Preparatory Sch, Orlando, FL USA
基金
美国国家科学基金会;
关键词
DNA logic gates; molecular beacon probes; rifampin; SNP analysis; tuberculosis; TIME PCR ASSAY; MYCOBACTERIUM-TUBERCULOSIS; XPERT MTB/RIF; SPECIES IDENTIFICATION; SNP ANALYSIS; PROBE; NANOTECHNOLOGY; PERFORMANCE; COMPUTATION; MUTATIONS;
D O I
10.1002/anie.201203708
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Elementary, Dr. Watson! A combination of YES and OR logic gates was applied to differentiate between DNA sequences of wild-type and rifampin-resistant (Rifr) Mycobacterium tuberculosis (Mtb) in a multiplex real-time fluorescent assay. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:9075 / 9077
页数:3
相关论文
共 49 条
[1]   Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics [J].
Abu-Raddad, Laith J. ;
Sabatelli, Lorenzo ;
Achterberg, Jerusha T. ;
Sugimoto, Jonathan D. ;
Longini, Ira M., Jr. ;
Dye, Christopher ;
Halloran, M. Elizabeth .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (33) :13980-13985
[2]  
[Anonymous], 2010, Multidrug and extensively drug-resistant TB(M/XDR-TB): 2010 Global Report on Surveillance and Response
[3]   Comparison of the Xpert MTB/RIF Test with an IS6110-TaqMan Real-Time PCR Assay for Direct Detection of Mycobacterium tuberculosis in Respiratory and Nonrespiratory Specimens [J].
Armand, Sylvie ;
Vanhuls, Pascale ;
Delcroix, Guy ;
Courcol, Rene ;
Lemaitre, Nadine .
JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (05) :1772-1776
[4]   An information-bearing seed for nucleating algorithmic self-assembly [J].
Barish, Robert D. ;
Schulman, Rebecca ;
Rothemund, Paul W. K. ;
Winfree, Erik .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (15) :6054-6059
[5]   Evaluation of the Analytical Performance of the Xpert MTB/RIF Assay [J].
Blakemore, Robert ;
Story, Elizabeth ;
Helb, Danica ;
Kop, JoAnn ;
Banada, Padmapriya ;
Owens, Michelle R. ;
Chakravorty, Soumitesh ;
Jones, Martin ;
Alland, David .
JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (07) :2495-2501
[6]   Rapid Universal Identification of Bacterial Pathogens from Clinical Cultures by Using a Novel Sloppy Molecular Beacon Melting Temperature Signature Technique [J].
Chakravorty, Soumitesh ;
Aladegbami, Bola ;
Burday, Michele ;
Levi, Michael ;
Marras, Salvatore A. E. ;
Shah, Darshini ;
El-Hajj, Hiyam H. ;
Kramer, Fred Russell ;
Alland, David .
JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (01) :258-267
[7]   Evaluation of a line probe assay kit for characterization of rpoB mutations in rifampin-resistant Mycobacterium tuberculosis isolates from new York City [J].
Cooksey, RC ;
Morlock, GP ;
Glickman, S ;
Crawford, JT .
JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (05) :1281-1283
[8]   ISOLATION OF THE GENE FOR THE BETA-SUBUNIT OF RNA-POLYMERASE FROM RIFAMPICIN-RESISTANT MYCOBACTERIUM-TUBERCULOSIS AND IDENTIFICATION OF NEW MUTATIONS [J].
DONNABELLA, V ;
MARTINIUK, F ;
KINNEY, D ;
BACERDO, M ;
BONK, S ;
HANNA, B ;
ROM, WN .
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1994, 11 (06) :639-643
[9]   Global burden of tuberculosis - Estimated incidence, prevalence, and mortality by country [J].
Dye, C ;
Scheele, S ;
Dolin, P ;
Pathania, V ;
Raviglione, RC .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (07) :677-686
[10]   Detection of rifampin resistance in Mycobacterium tuberculosis in a single tube with molecular beacons [J].
El-Hajj, HH ;
Marras, SAE ;
Tyagi, S ;
Kramer, FR ;
Alland, D .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (11) :4131-4137