Aspirin in the primary prevention of colorectal cancer

被引:0
作者
Fernandez-Calderon, M. [1 ]
Betes Ibanez, M. T. [1 ]
机构
[1] Univ Navarra Clin, Dept Digest, Pamplona 31008, Spain
关键词
Aspirin; Colorectal cancer; Prevention; FAMILIAL ADENOMATOUS POLYPOSIS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; RANDOMIZED-TRIALS; CYCLOOXYGENASE-2; INHIBITOR; FOLLOW-UP; RISK; CHEMOPREVENTION; METAANALYSIS; RECURRENCE; CELECOXIB;
D O I
10.4321/S1137-66272012000200008
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have been associated with a reduction in the risk of developing adenomas and colorectal cancer. The available scientific evidence justifies the need for more studies that evaluate the protective effect of aspirin and other NSAIDs as a preventive measure against cancer of the colon; define the minimum efficient dosage; the age at which to begin treatment; the most convenient duration of the latter; and the sub-populations for which the benefits of chemoprophylaxis outweigh possible adverse effects.
引用
收藏
页码:261 / 267
页数:7
相关论文
共 28 条
  • [1] ALONSO SANCHEZ A, 2006, AN SIST SANIT NAVAR, V29, P59
  • [2] Baigent C, 2002, BMJ-BRIT MED J, V324, P71, DOI 10.1136/bmj.324.7329.71
  • [3] A randomized trial of aspirin to prevent colorectal adenomas
    Baron, JA
    Cole, BF
    Sandler, RS
    Haile, RW
    Ahnen, D
    Bresalier, R
    McKeown-Eyssen, G
    Summers, RW
    Rothstein, R
    Burke, CA
    Snover, DC
    Church, TR
    Allen, JI
    Beach, M
    Beck, GJ
    Bond, JH
    Byers, T
    Greenberg, ER
    Mandel, JS
    Marcon, N
    Mott, LA
    Pearson, L
    Saibil, F
    van Stolk, RU
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (10) : 891 - 899
  • [4] Daily soluble aspirin and prevention of colorectal adenoma recurrence: One-year results of the APACC trial
    Benamouzig, R
    Deyra, J
    Martin, A
    Girard, B
    Jullian, E
    Piednoir, B
    Couturier, D
    Coste, T
    Little, J
    Chaussade, S
    [J]. GASTROENTEROLOGY, 2003, 125 (02) : 328 - 336
  • [5] Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention
    Benamouzig, Robert
    Uzzan, Bernard
    Martin, Antoine
    Deyra, Jacques
    Little, Julian
    Girard, Bernard
    Chaussade, Stanislas
    [J]. GUT, 2010, 59 (05) : 622 - 629
  • [6] Celecoxib for the prevention of sporadic colorectal adenomas
    Bertagnolli, Monica M.
    Eagle, Craig J.
    Zauber, Ann G.
    Redston, Mark
    Solomon, Scott D.
    Kim, KyungMann
    Tang, Jie
    Rosenstein, Rebecca B.
    Wittes, Janet
    Corle, Donald
    Hess, Timothy M.
    Woloj, G. Mabel
    Boisserie, Frederic
    Anderson, William F.
    Viner, Jaye L.
    Bagheri, Donya
    Burn, John
    Chung, Daniel C.
    Dewar, Thomas
    Foley, T. Raymond
    Hoffman, Neville
    Macrae, Finlay
    Pruitt, Ronald E.
    Saltzman, John R.
    Salzberg, Bruce
    Sylwestrowicz, Thomas
    Gordon, Gary B.
    Hawk, Ernest T.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (09) : 873 - 884
  • [7] Betes M, 2006, EVIDENCIA CIENTIFICA
  • [8] BURN J, 2010, HERED CANC CLIN P S1, V8, pO5
  • [9] Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial
    Burn, John
    Gerdes, Anne-Marie
    Macrae, Finlay
    Mecklin, Jukka-Pekka
    Moeslein, Gabriela
    Olschwang, Sylviane
    Eccles, Diane
    Evans, D. Gareth
    Maher, Eamonn R.
    Bertario, Lucio
    Bisgaard, Marie-Luise
    Dunlop, Malcolm G.
    Ho, Judy W. C.
    Hodgson, Shirley V.
    Lindblom, Annika
    Lubinski, Jan
    Morrison, Patrick J.
    Murday, Victoria
    Ramesar, Raj
    Side, Lucy
    Scott, Rodney J.
    Thomas, Huw J. W.
    Vasen, Hans F.
    Barker, Gail
    Crawford, Gillian
    Elliott, Faye
    Movahedi, Mohammad
    Pylvanainen, Kirsi
    Wijnen, Juul T.
    Fodde, Riccardo
    Lynch, Henry T.
    Mathers, John C.
    Bishop, D. Timothy
    [J]. LANCET, 2011, 378 (9809) : 2081 - 2087
  • [10] Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome
    Burn, John
    Bishop, D. Timothy
    Mecklin, Jukka-Pekka
    Macrae, Finlay
    Moeslein, Gabriela
    Olschwang, Sylviane
    Bisgaard, Marie-Luise
    Ramesar, Raj
    Eccles, Diana
    Maher, Eamonn R.
    Bertario, Lucio
    Jarvinen, Heikki J.
    Lindblom, Annika
    Evans, D. Gareth
    Lubinski, Jan
    Morrison, Patrick J.
    Ho, Judy W. C.
    Vasen, Hans F. A.
    Side, Lucy
    Thomas, Huw J. W.
    Scott, Rodney J.
    Dunlop, Malcolm
    Barker, Gail
    Elliott, Faye
    Jass, Jeremy R.
    Fodde, Ricardo
    Lynch, Henry T.
    Mathers, John C.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (24) : 2567 - 2578