A new aromatic glucoside from stem bark of Illicium difengpi KIB et KIM

被引：13
作者：
Li, Chuntong [1 ,2 ]
Wu, Zhijun [2 ]
Chen, Wansheng [2 ]
机构：
[1] Peoples Liberat Army Gen Hosp, Dept Pharm & Pharmacol, Affiliated Hosp 1, Beijing 100048, Peoples R China
[2] Second Mil Med Univ, Changzheng Hosp, Dept Pharm, Shanghai 200003, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2015年 / 29卷 / 19期
关键词：
Illicium difengpi; anti-inflammatory; aromatic glucoside; CHEMICAL-CONSTITUENTS;
D O I：
10.1080/14786419.2015.1004675
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new aromatic glucoside, namely 4-methoxyphenyl-(6-deoxy--L-mannopyranosyl)--D-glucopyranoside (1), together with six known aromatic glucosides (2-7) were isolated from the stem bark of Illicium difengpi. The structures of these compounds were established by spectroscopic methods. The isolated aromatic glucosides were tested for anti-inflammatory activity. Compounds 1, 3 and 6 showed significant inhibitory effect on nuclear factor kappa B (NF-B) in RAW 264.7 macrophages induced by lipopolysaccharide.
引用
收藏
页码：1793 / 1797
页数：5
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