Evaluation of Clinical Outcomes and Bone Loss around Titanium Implants with Oxidized Surface: Six-Year Follow-Up Results from a Prospective Case Series Study

Purpose: The aim of this prospective study was to assess long-term clinical outcomes and peri-implant bone level changes around oxidized implants supporting partial fixed rehabilitations. Materials and Methods: Twenty-two partially edentulous patients were included in the study. A total of 33 fixed rehabilitations were placed, supported by 54 titanium implants with oxidized microtextured surface. Prostheses were delivered after 3 and 6 months of implant placement in the mandible and maxilla, respectively. Patients were scheduled for follow-up at 6 and 12 months and then yearly. At each follow-up, plaque level and bleeding scores were assessed and periapical radiographs were taken. The main outcomes were prosthesis success, implant survival, implant success, and marginal bone level change. Results: Three patients were excluded from the study because they did not attend the 1-year follow-up. Nineteen patients, accounting for 49 implants, were followed for at least 6 years after prosthesis delivery. The mean follow-up duration was 81.8 months (range 75-96 months). One mandibular single-tooth implant failed after 1 year in a smoker woman. Cumulative implant survival and success at 6 years were 98.0% and 95.9%, respectively. Prosthesis success was 96.7%. The mean peri-implant bone loss at 6 years was 0.760.47mm. Not significantly (p=.75) greater bone loss was found in the maxilla (0.78 +/- 0.14mm, n=19) as compared with the mandible (0.74 +/- 0.59mm, n=30). In the maxilla, bone loss was significantly greater around implants supporting partial prostheses as compared with single-tooth implants (p=.03). Full patient satisfaction was reported. Conclusion: Implants with oxidized microtextured surface may achieve excellent long-term clinical outcomes in the rehabilitation of partial edentulism.