Fluorescent silver nanoclusters as DNA probes

被引:133
|
作者
Obliosca, Judy M. [1 ]
Liu, Cong [1 ]
Yeh, Hsin-Chih [1 ]
机构
[1] Univ Texas Austin, Dept Biomed Engn, Austin, TX 78712 USA
关键词
SINGLE-NUCLEOTIDE POLYMORPHISMS; NUCLEIC-ACID HYBRIDIZATION; PHOTOINDUCED ELECTRON-TRANSFER; GUANINE-GUANINE MISMATCHES; LABEL-FREE; MOLECULAR BEACONS; MUTATION DETECTION; AG NANOCLUSTERS; ENERGY-TRANSFER; COLORIMETRIC DETECTION;
D O I
10.1039/c3nr01601c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Fluorescent silver nanoclusters (few atoms, quantum sized) have attracted much attention as promising substitutes for conventional fluorophores. Due to their unique environmental sensitivities, new fluorescent probes have been developed based on silver nanoclusters for the sensitive and specific detection of DNA. In this review we present the recent discoveries of activatable and color-switchable properties of DNA-templated silver nanoclusters and discuss the strategies to use these new properties in DNA sensing.
引用
收藏
页码:8443 / 8461
页数:19
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