ULTRASOUND-MEDIATED SYNTHESIS OF 3,4-DIHYDROPYRIMIDIN-2-(1H)-ONES (OR THIONES) WITH NaHSO4•H2O

被引：19

作者：

Dilmaghani, Karim Akbari ^{[1
]}

Zeynizadeh, Behzad ^{[1
]}

Amirpoor, Maryam ^{[1
]}

机构：

[1] Urmia Univ, Fac Sci, Dept Chem, Orumiyeh 57159165, Iran

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2013年 / 188卷 / 11期

关键词：

3; 4-Dihydropyrimidin-2-(1H)-ones; aldehydes; -dicarbonyls; NaHSO4 center dot H2O; ultrasound; ONE-POT SYNTHESIS; IMPROVED PROTOCOL CONDITIONS; SOLVENT-FREE; EFFICIENT SYNTHESIS; SULFUR DERIVATIVES; REUSABLE CATALYST; CONDENSATION REACTION; RECYCLABLE CATALYST; ASSISTED SYNTHESIS; BIGINELLI REACTION;

D O I：

10.1080/10426507.2013.777725

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A fast and efficient Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-ones (or thiones) by the reaction of aromatic aldehydes, -dicarbonyls, and urea/thiourea using NaHSO4H2O/ultrasound system is presented. The reactions were carried out in refluxing n-hexane/CH3CN (2.5:0.5mL) to afford the products in excellent yields.

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页码：1634 / 1642

页数：9

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