Adult pallium transcriptomes surprise in not reflecting predicted homologies across diverse chicken and mouse pallial sectors

被引：65

作者：

Belgard, T. Grant ^{[1
,2
]}

Montiel, Juan F. ^{[3
,4
]}

Wang, Wei Zhi ^{[3
]}

Garcia-Moreno, Fernando ^{[3
]}

Margulies, Elliott H. ^{[2
]}

Ponting, Chris P. ^{[1
]}

Molnar, Zoltan ^{[3
]}

机构：

[1] Univ Oxford, MRC, Funct Genom Unit, Dept Physiol Anat & Genet, Oxford OX1 3PT, England

[2] NHGRI, NIH, Bethesda, MD 20892 USA

[3] Univ Oxford, Dept Physiol Anat & Genet, Oxford OX1 3QX, England

[4] Univ Diego Portales, Fac Med, Ctr Biomed Res, Santiago 8370068, Chile

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2013年 / 110卷 / 32期

基金：

英国生物技术与生命科学研究理事会; 欧洲研究理事会; 英国医学研究理事会;

关键词：

cerebral cortex; Wulst; equivalent circuit hypothesis; brain evolution; dorsal ventricular ridge; EVOLUTION; NEOCORTEX; BRAIN; EXPRESSION; ORIGINS; CORTEX; TELENCEPHALON; AMNIOTES; PATTERNS;

D O I：

10.1073/pnas.1307444110

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The thorniest problem in comparative neurobiology is the identification of the particular brain region of birds and reptiles that corresponds to the mammalian neocortex [Butler AB, Reiner A, Karten HJ (2011) Ann N Y Acad Sci 1225:14-27; Wang Y, Brzozowska-Prechtl A, Karten HJ (2010) Proc Natl Acad Sci USA 107(28):12676-12681]. We explored which genes are actively transcribed in the regions of controversial ancestry in a representative bird (chicken) and mammal (mouse) at adult stages. We conducted four analyses comparing the expression patterns of their 5,130 most highly expressed one-to-one orthologous genes that considered global patterns of expression specificity, strong gene markers, and coexpression networks. Our study demonstrates transcriptomic divergence, plausible convergence, and, in two exceptional cases, conservation between specialized avian and mammalian telencephalic regions. This large-scale study potentially resolves the complex relationship between developmental homology and functional characteristics on the molecular level and settles long-standing evolutionary debates.

引用

页码：13150 / 13155

页数：6

共 23 条

[1] The evolutionary origin of the mammalian isocortex: Towards an integrated developmental and functional approach [J].

Aboitiz, F ;

Morales, D ;

Montiel, J .

BEHAVIORAL AND BRAIN SCIENCES, 2003, 26 (05) :535-+

[2] A Transcriptomic Atlas of Mouse Neocortical Layers [J].

Belgard, T. Grant ;

Marques, Ana C. ;

Oliver, Peter L. ;

Abaan, Hatice Ozel ;

Sirey, Tamara M. ;

Hoerder-Suabedissen, Anna ;

Garcia-Moreno, Fernando ;

Molnar, Zoltan ;

Margulies, Elliott H. ;

Ponting, Chris P. .

NEURON, 2011, 71 (04) :605-616

[3] Transcriptional Architecture of the Primate Neocortex [J].

Bernard, Amy ;

Lubbers, Laura S. ;

Tanis, Keith Q. ;

Luo, Rui ;

Podtelezhnikov, Alexei A. ;

Finney, Eva M. ;

McWhorter, Mollie M. E. ;

Serikawa, Kyle ;

Lemon, Tracy ;

Morgan, Rebecca ;

Copeland, Catherine ;

Smith, Kimberly ;

Cullen, Vivian ;

Davis-Turak, Jeremy ;

Lee, Chang-Kyu ;

Sunkin, Susan M. ;

Loboda, Andrey P. ;

Levine, David M. ;

Stone, David J. ;

Hawrylycz, Michael J. ;

Roberts, Christopher J. ;

Jones, Allan R. ;

Geschwind, Daniel H. ;

Lein, Ed S. .

NEURON, 2012, 73 (06) :1083-1099

[4] Evolution of the amniote pallium and the origins of mammalian neocortex [J].

Butler, Ann B. ;

Reiner, Anton ;

Karten, Harvey J. .

NEW PERSPECTIVES ON NEUROBEHAVIORAL EVOLUTION, 2011, 1225 :14-27

[5] Is the avian hippocampus a functional homologue of the mammalian hippocampus? [J].

Colombo, M ;

Broadbent, N .

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2000, 24 (04) :465-484

[6] Cell-type homologies and the origins of the neocortex [J].

Dugas-Ford, Jennifer ;

Rowell, Joanna J. ;

Ragsdale, Clifton W. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (42) :16974-16979

[7]

Fernandez AS, 1998, DEVELOPMENT, V125, P2099

[8] The convergent evolution of neural substrates for cognition [J].

Guentuerkuen, Onur .

PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG, 2012, 76 (02) :212-219

[9] Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target [J].

Horvath, S. ;

Zhang, B. ;

Carlson, M. ;

Lu, K. V. ;

Zhu, S. ;

Felciano, R. M. ;

Laurance, M. F. ;

Zhao, W. ;

Qi, S. ;

Chen, Z. ;

Lee, Y. ;

Scheck, A. C. ;

Liau, L. M. ;

Wu, H. ;

Geschwind, D. H. ;

Febbo, P. G. ;

Kornblum, H. I. ;

Cloughesy, T. F. ;

Nelson, S. F. ;

Mischel, P. S. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (46) :17402-17407

[10] RORβ Induces Barrel-like Neuronal Clusters in the Developing Neocortex [J].

Jabaudon, Denis ;

Shnider, Sara J. ;

Tischfield, David J. ;

Galazo, Maria J. ;

Macklis, Jeffrey D. .

CEREBRAL CORTEX, 2012, 22 (05) :996-1006

← 1 2 3 →