New Method of Genome Editing Derived From CRISPR/Cas9

被引：3

作者：

Fang Rui ^{[1
]}

Chang Fei ^{[1
]}

Sun Zhao-Lin ^{[1
]}

Li Ning ^{[1
]}

Meng Qing-Yong ^{[1
]}

机构：

[1] China Agr Univ, State Key Lab Agrobiotechnol, Beijing 100193, Peoples R China

来源：

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 2013年 / 40卷 / 08期

关键词：

CRISPR/Cas9; gene targeting; genome editing technology; engineered endonuclease; HORIZONTAL GENE-TRANSFER; ZINC-FINGER NUCLEASES; IMMUNE-SYSTEM; ESCHERICHIA-COLI; RNA; DNA; SEQUENCE; REPEATS; TRANSCRIPTION; RESISTANCE;

D O I：

10.3724/SP.J.1206.2013.00215

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The type II clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas)9 system has been used as a gene-targeting technology as ZFN and TALEN to meditate multiple genome editing. Unlike ZFN and TALEN directly binding to the specific DNA sequence to generate a double-strands break, the engineered CRISPR/Cas9 system has been demonstrated that Cas9 nuclease was directed by short RNAs to induce site-specific cleavage in complex genome. The advantage of CRPSR/Cas9 system is easy to be constructed and low cost compared with ZFN and TALEN. So, it is considered that it will replace existing technique. Here we review the CRISPR/Cas development history, classification, mechanism, progress and application of this new genome editing technology. This review will provide a useful reference for researchers who are interested in applying this new technique in their studies.

引用

页码：691 / 702

页数：12

共 79 条

[11] Efficient TALEN-mediated gene knockout in livestock [J].

Carlson, Daniel F. ;

Tan, Wenfang ;

Lillico, Simon G. ;

Stverakova, Dana ;

Proudfoot, Chris ;

Christian, Michelle ;

Voytas, Daniel F. ;

Long, Charles R. ;

Whitelaw, C. Bruce A. ;

Fahrenkrug, Scott C. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (43) :17382-17387

[12] Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos [J].

Chang, Nannan ;

Sun, Changhong ;

Gao, Lu ;

Zhu, Dan ;

Xu, Xiufei ;

Zhu, Xiaojun ;

Xiong, Jing-Wei ;

Xi, Jianzhong Jeff .

CELL RESEARCH, 2013, 23 (04) :465-472

[13] A large-scale in vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly [J].

Chen, Shijia ;

Oikonomou, Grigorios ;

Chiu, Cindy N. ;

Niles, Brett J. ;

Liu, Justin ;

Lee, Daniel A. ;

Antoshechkin, Igor ;

Prober, David A. .

NUCLEIC ACIDS RESEARCH, 2013, 41 (04) :2769-2778

[14] A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep [J].

Clop, Alex ;

Marcq, Fabienne ;

Takeda, Haruko ;

Pirottin, Dimitri ;

Tordoir, Xavier ;

Bibe, Bernard ;

Bouix, Jacques ;

Caiment, Florian ;

Elsen, Jean-Michel ;

Eychenne, Francis ;

Larzul, Catherine ;

Laville, Elisabeth ;

Meish, Francoise ;

Milenkovic, Dragan ;

Tobin, James ;

Charlier, Carole ;

Georges, Michel .

NATURE GENETICS, 2006, 38 (07) :813-818

[15] Multiplex Genome Engineering Using CRISPR/Cas Systems [J].

Cong, Le ;

Ran, F. Ann ;

Cox, David ;

Lin, Shuailiang ;

Barretto, Robert ;

Habib, Naomi ;

Hsu, Patrick D. ;

Wu, Xuebing ;

Jiang, Wenyan ;

Marraffini, Luciano A. ;

Zhang, Feng .

SCIENCE, 2013, 339 (6121) :819-823

[16] CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III [J].

Deltcheva, Elitza ;

Chylinski, Krzysztof ;

Sharma, Cynthia M. ;

Gonzales, Karine ;

Chao, Yanjie ;

Pirzada, Zaid A. ;

Eckert, Maria R. ;

Vogel, Joerg ;

Charpentier, Emmanuelle .

NATURE, 2011, 471 (7340) :602-+

[17] Phage response to CRISPR-Encoded resistance in Streptococcus thermophilus [J].

Deveau, Helene ;

Barrangou, Rodolphe ;

Garneau, Josiane E. ;

Labonte, Jessica ;

Fremaux, Christophe ;

Boyaval, Patrick ;

Romero, Dennis A. ;

Horvath, Philippe ;

Moineau, Sylvain .

JOURNAL OF BACTERIOLOGY, 2008, 190 (04) :1390-1400

[18] CRISPR/Cas System and Its Role in Phage-Bacteria Interactions [J].

Deveau, Helene ;

Garneau, Josiane E. ;

Moineau, Sylvain .

ANNUAL REVIEW OF MICROBIOLOGY, VOL 64, 2010, 2010, 64 :475-493

[19] Enhanced Efficiency of Human Pluripotent Stem Cell Genome Editing through Replacing TALENs with CRISPRs [J].

Ding, Qiurong ;

Regan, Stephanie N. ;

Xia, Yulei ;

Oostrom, Leonie A. ;

Cowan, Chad A. ;

Musunuru, Kiran .

CELL STEM CELL, 2013, 12 (04) :393-394

[20] The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA [J].

Garneau, Josiane E. ;

Dupuis, Marie-Eve ;

Villion, Manuela ;

Romero, Dennis A. ;

Barrangou, Rodolphe ;

Boyaval, Patrick ;

Fremaux, Christophe ;

Horvath, Philippe ;

Magadan, Alfonso H. ;

Moineau, Sylvain .

NATURE, 2010, 468 (7320) :67-71

← 1 2 3 4 5 6 7 8 →