Two-step synthesis of the bipyrrole precursor of prodigiosins

被引：63

作者：

Dairi, K ^{[1
]}

Tripathy, S ^{[1
]}

Attardo, G ^{[1
]}

Lavallée, JF ^{[1
]}

机构：

[1] Gemin X Biotechnol Inc, Dept Med Chem, Montreal, PQ H2X 2H7, Canada

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 15期

关键词：

natural product; prodigiosins; tambjamines; haloformylation; bipyrrole; Suzuki coupling;

D O I：

10.1016/j.tetlet.2006.02.035

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The key intermediate in the synthesis of prodigiosins, 4-methoxy-2,2'-bipyrrole-5-carboxaldehyde, has been prepared in two steps and 65% overall yield from the commercially available 4-methoxy-3-pyrrolin-2-one. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：2605 / 2606

页数：2

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