Pure primary squamous cell carcinoma of the ovary

Ovarian squamous cell carcinoma is a rare malignant neoplasm; its occurrence is attributable to malignant transformation of an existing ovarian tumor. The pure variety of ovarian squamous cell carcinoma, in the absence of pre-existing ovarian lesions including dermoid cysts, Brenner's tumors or endometriosis, is extremely rare and is considered a metaplasia of the surface epithelium. Because of its rarity, clinical features and effective treatments have not been established. Adequate evaluation prior to surgery is critical to determine the extent of surgery and adjuvant therapy. There is no agreement on postoperative chemotherapy or radiotherapy. The prognosis of advanced disease is generally poor. A case of pure primary squamous cell carcinoma of the ovary is presented.