Development of calixarene-based host molecules for peptides in aqueous media

被引：12

作者：

Kubo, M ^{[1
]}

Nashimoto, E ^{[1
]}

Tokiyo, T ^{[1
]}

Morisaki, Y ^{[1
]}

Kodama, M ^{[1
]}

Hioki, H ^{[1
]}

机构：

[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 12期

关键词：

calixarene; combinatorial library; recognition in aqueous media;

D O I：

10.1016/j.tetlet.2006.01.078

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We synthesized a peptidocalix[4]arene library consisting of 1000 members that was suitable for peptide recognition in aqueous media. Some peptidocalix[4]arenes in the library were host molecules for guest peptides. Electrostatic interaction between the host and guest molecules was the most important factor for binding in aqueous media. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：1927 / 1931

页数：5

共 20 条

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