Current status of perioperative temporary mechanical circulatory support during cardiac surgery

被引:4
作者
Minhas, Abdul Mannan Khan [1 ]
Abramov, Dmitry [2 ]
Chung, Joshua S. [3 ]
Patel, Jay [4 ]
Mamas, Mamas A. [5 ]
Zieroth, Shelley [6 ]
Agarwal, Richa [7 ]
Fudim, Marat [7 ,8 ]
Rabkin, David G. [3 ]
机构
[1] Forrest Gen Hosp, Div Med, Hattiesburg, MS USA
[2] Loma Linda Univ, Dept Med, Div Cardiol, Med Ctr, Loma Linda, CA 92354 USA
[3] Loma Linda Univ, Med Ctr, Dept Cardiothorac Surg, Coleman Pavilion,11175 Campus St,Suite 21121, Loma Linda, CA 92354 USA
[4] Loma Linda Vet Adm Healthcare Syst, Loma Linda, CA USA
[5] Keele Univ, Keele Cardiovasc Res Grp, Stoke On Trent, Staffs, England
[6] Univ Manitoba, Dept Med, Sect Cardiol, Winnipeg, MB, Canada
[7] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA
[8] Duke Clin Res Inst, Durham, NC USA
关键词
cardiac surgery; mechanical circulatory support; perioperative management; EXTRACORPOREAL MEMBRANE-OXYGENATION; OUTCOMES;
D O I
10.1111/jocs.17020
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives We sought to determine utilization and outcomes of perioperative temporary mechanical circulatory support (tMCS) in the current practice of cardiac surgery. Background tMCS is an evolving adjunct to cardiac surgery not fully characterized in contemporary practice. Methods Using the nationwide inpatient sample we retrospectively analyzed hospital discharge data between January 1, 2016 and December 31, 2019. ICD-10-CM procedure codes were used to identify and divide patient hospitalizations into those who had preoperative tMCS (pre-tMCS) versus tMCS instituted the day of surgery or afterwards (sd/post-tMCS). Results In all, 1,383,520 hospitalizations met inclusion criteria. 86,445 (6.25%) had tMCS. tMCS was utilized in 8.74% of coronary artery bypass grafting (CABG), 2.58% of isolated valve, and 9.71% of valve/CABG; operations. 29,325 (33.9%) had pre-tMCS while 57,120 (66.1%) had sd/post-tMCS. The use of tMCS was associated with greater inpatient mortality (15.66% vs. 1.53%, p < .001), longer length of stay (LOS) (14.4 vs. 8.5 days, p < .001), and higher mean inflation-adjusted costs ($93,040 +/- 1038 vs. $51,358 +/- 296, p < .001) compared to no use. Inpatient mortality (5.98% vs. 20.63%, p < .001), LOS (13.87 vs. 14.68, p < .001), and cost ($82,621 +/- 1152 SEM vs. $98,381 +/- 1242) were all significantly lower with pre-tMCS compared to sd/post tMCS. When analyzed separately, mortality was higher with later utilization of tMCS (5.98% pre, 17.1% sd, and 49.05% postsurgical date insertion, p < .001). Conclusions Perioperative tMCS is utilized in 6.25% of modern cardiac surgery, with two-thirds of cases instituted on the day of surgery or afterwards. The use of tMCS is associated with significantly higher mortality, longer LOS, and higher costs. Among patients undergoing tMCS, earlier utilization is associated with better outcomes.
引用
收藏
页码:4304 / 4315
页数:12
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