How Our Other Genome Controls Our Epi-Genome

被引：62

作者：

Celluzzi, Antonella ^{[1
]}

Masotti, Andrea ^{[1
]}

机构：

[1] Bambino Gesu Childrens Hosp IRCCS, Gene Express Microarrays Lab, Viale San Paolo 15, I-00146 Rome, Italy

来源：

TRENDS IN MICROBIOLOGY | 2016年 / 24卷 / 10期

关键词：

BACTERIAL OUTER-MEMBRANE; LONG NONCODING RNAS; GUT MICROBIOTA; PSEUDOMONAS-AERUGINOSA; EXTRACELLULAR VESICLES; MICRORNA-SIZE; TERM-MEMORY; HEALTH; MODULATION; RELEASE;

D O I：

10.1016/j.tim.2016.05.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Eukaryotes and prokaryotes produce extracellular nanovescicles that contain RNAs and other molecules that they exploit to communicate. Recently, inter kingdom crosstalk was demonstrated between humans and bacteria through fecal microRNAs. We suggest here how bacteria interact with humans via RNAs within membrane vesicles to alter our epigenome, thus filling the gap and closing the circle. At the same time, there are indications that there could be a wider inter kingdom communication network that might encompass all known kingdoms. Now that the connection with our other genome has been established, we also should begin to explore the 'social' network that we have around us.

引用

页码：777 / 787

页数：11

共 60 条

[1] Microbial Hub Taxa Link Host and Abiotic Factors to Plant Microbiome Variation [J].

Agler, Matthew T. ;

Ruhe, Jonas ;

Kroll, Samuel ;

Morhenn, Constanze ;

Kim, Sang-Tae ;

Weigel, Detlef ;

Kemen, Eric M. .

PLOS BIOLOGY, 2016, 14 (01)

[2] Human Microbiome and its Association With Health and Diseases [J].

Althani, Asmaa A. ;

Marei, Hany E. ;

Hamdi, Wedad S. ;

Nasrallah, Gheyath K. ;

El Zowalaty, Mohamed E. ;

Al Khodor, Souhaila ;

Al-Asmakh, Maha ;

Abdel-Aziz, Hassan ;

Cenciarelli, Carlo .

JOURNAL OF CELLULAR PHYSIOLOGY, 2016, 231 (08) :1688-1694

[3] Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma [J].

Arroyo, Jason D. ;

Chevillet, John R. ;

Kroh, Evan M. ;

Ruf, Ingrid K. ;

Pritchard, Colin C. ;

Gibson, Donald F. ;

Mitchell, Patrick S. ;

Bennett, Christopher F. ;

Pogosova-Agadjanyan, Era L. ;

Stirewalt, Derek L. ;

Tait, Jonathan F. ;

Tewari, Muneesh .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (12) :5003-5008

[4] Purification of outer membrane vesicles from Pseudomonas aeruginosa and their activation of an IL-8 response [J].

Bauman, Susanne J. ;

Kuehn, Meta J. .

MICROBES AND INFECTION, 2006, 8 (9-10) :2400-2408

[5] Structures of gram-negative cell walls and their derived membrane vesicles [J].

Beveridge, TJ .

JOURNAL OF BACTERIOLOGY, 1999, 181 (16) :4725-4733

[6] The intestinal microbiota: its role in health and disease [J].

Biedermann, Luc ;

Rogler, Gerhard .

EUROPEAN JOURNAL OF PEDIATRICS, 2015, 174 (02) :151-167

[7]

Bieme H., 2012, COLD SPRING HARB PER, V2

[8] Bacterial Vesicles in Marine Ecosystems [J].

Biller, Steven J. ;

Schubotz, Florence ;

Roggensack, Sara E. ;

Thompson, Anne W. ;

Summons, Roger E. ;

Chisholm, Sallie W. .

SCIENCE, 2014, 343 (6167) :183-186

[9] Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi [J].

Brown, Lisa ;

Wolf, Julie M. ;

Prados-Rosales, Rafael ;

Casadevall, Arturo .

NATURE REVIEWS MICROBIOLOGY, 2015, 13 (10) :620-630

[10] Gut microbiota modulation: probiotics, antibiotics or fecal microbiota transplantation? [J].

Cammarota, Giovanni ;

Ianiro, Gianluca ;

Bibbo, Stefano ;

Gasbarrini, Antonio .

INTERNAL AND EMERGENCY MEDICINE, 2014, 9 (04) :365-373

← 1 2 3 4 5 6 →