Studying c-Myc serine 62 phosphorylation in leukemia cells: concern over antibody cross-reactivity

被引：2

作者：

Tibbitts, Deanne C. ^{[1
]}

Escamilla-Powers, Julienne R. ^{[1
]}

Zhang, Xiaoli ^{[1
]}

Sears, Rosalie C. ^{[1
]}

机构：

[1] Oregon Hlth & Sci Univ, Dept Mol & Med Genet, Portland, OR 97239 USA

来源：

BLOOD | 2012年 / 119卷 / 22期

关键词：

PROTEIN STABILITY; STABILIZATION; PATHWAY;

D O I：

10.1182/blood-2012-03-414532

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：5334 / 5335

页数：2

共 9 条

[1] Protein phosphatase 2A regulatory subunit b56α associates with c-Myc and negatively regulates c-Myc accumulation [J].

Arnold, HK ;

Sears, RC .

MOLECULAR AND CELLULAR BIOLOGY, 2006, 26 (07) :2832-2844

[2] c-Myc phosphorylation is required for cellular response to oxidative stress [J].

Benassi, B ;

Fanciulli, M ;

Fiorentino, F ;

Porrello, A ;

Chiorino, G ;

Loda, M ;

Zupi, G ;

Biroccio, A .

MOLECULAR CELL, 2006, 21 (04) :509-519

[3] Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia [J].

Chen, Lisa S. ;

Redkar, Sanjeev ;

Taverna, Pietro ;

Cortes, Jorge E. ;

Gandhi, Varsha .

BLOOD, 2011, 118 (03) :693-702

[4] A conserved pathway that controls c-Myc protein stability through opposing phosphorylation events occurs in yeast [J].

Escamilia-Powers, Julienne R. ;

Sears, Rosalie C. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (08) :5432-5442

[5] Phosphorylation by Cdk2 is required for Myc to repress Ras-induced senescence in cotransformation [J].

Hydbring, Per ;

Bahram, Fuad ;

Su, Yingtao ;

Tronnersjo, Susanna ;

Hogstrand, Kari ;

von der Lehr, Natalie ;

Sharifi, Hamid Reza ;

Lilischkis, Richard ;

Hein, Nadine ;

Wu, Siqin ;

Vervoorts, Jorg ;

Henriksson, Marie ;

Grandien, Alf ;

Luscher, Bernhard ;

Larsson, Lars-Gunnar .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (01) :58-63

[6] Aberrant stabilization of c-Myc protein in some lymphoblastic leukemias [J].

Malempati, S. ;

Tibbitts, D. ;

Cunningham, M. ;

Akkari, Y. ;

Olson, S. ;

Fan, G. ;

Sears, R. C. .

LEUKEMIA, 2006, 20 (09) :1572-1581

[7] Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability [J].

Sears, R ;

Nuckolls, F ;

Haura, E ;

Taya, Y ;

Tamai, K ;

Nevins, JR .

GENES & DEVELOPMENT, 2000, 14 (19) :2501-2514

[8] A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells [J].

Yeh, E ;

Cunningham, M ;

Arnold, H ;

Chasse, D ;

Monteith, T ;

Ivaldi, G ;

Hahn, WC ;

Stukenberg, PT ;

Shenolikar, S ;

Uchida, T ;

Counter, CM ;

Nevins, JR ;

Means, AR ;

Sears, R .

NATURE CELL BIOLOGY, 2004, 6 (04) :308-318

[9] Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression [J].

Zhang, Xiaoli ;

Farrell, Amy S. ;

Daniel, Colin J. ;

Arnold, Hugh ;

Scanlan, Charles ;

Laraway, Bryan J. ;

Janghorban, Mahnaz ;

Lum, Lawrence ;

Chen, Dexi ;

Troxell, Megan ;

Sears, Rosalie .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (08) :2790-2795

← 1 →