Biological Applications of Silica-Based Nanoparticles

被引：39

作者：

Bruckmann, Franciele da Silva ^{[1
]}

Nunes, Franciane Batista ^{[1
]}

Salles, Theodoro da Rosa ^{[1
]}

Franco, Camila ^{[2
]}

Cadona, Francine Carla ^{[2
]}

Bohn Rhoden, Cristiano Rodrigo ^{[1
,3
]}

机构：

[1] Univ Franciscana UFN, Lab Mat Magnet LaMMaN, BR-97010030 Santa Maria, RS, Brazil

[2] Univ Franciscana UFN, Ciencias Saude & Vida, BR-97010030 Santa Maria, RS, Brazil

[3] Univ Franciscana UFN, Programa Posgrad Nanociencias, BR-97010030 Santa Maria, RS, Brazil

来源：

MAGNETOCHEMISTRY | 2022年 / 8卷 / 10期

关键词：

magnetic nanoparticles; multifunctional systems; nanocarriers; MAGNETIC MESOPOROUS SILICA; IRON-OXIDE NANOPARTICLES; CORE-SHELL; HYPERTHERMIA; ANTICANCER; THERAPY; CYTOTOXICITY; NANOCOMPOSITES; NANOMATERIAL; FLUORESCENCE;

D O I：

10.3390/magnetochemistry8100131

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Silica nanoparticles have been widely explored in biomedical applications, mainly related to drug delivery and cancer treatment. These nanoparticles have excellent properties, high biocompatibility, chemical and thermal stability, and ease of functionalization. Moreover, silica is used to coat magnetic nanoparticles protecting against acid leaching and aggregation as well as increasing cytocompatibility. This review reports the recent advances of silica-based magnetic nanoparticles focusing on drug delivery, drug target systems, and their use in magnetohyperthermia and magnetic resonance imaging. Notwithstanding, the application in other biomedical fields is also reported and discussed. Finally, this work provides an overview of the challenges and perspectives related to the use of silica-based magnetic nanoparticles in the biomedical field.

引用

页数：28

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