Neurodevelopment in children with intrauterine growth restriction: adverse effects and interventions

被引：41

作者：

Wang, Yan ^{[1
,2
]}

Fu, Wei ^{[1
]}

Liu, Jing ^{[1
]}

机构：

[1] Beijing Mil Gen Hosp, Dept Neonatol & NICU, Bayi Childrens Hosp, Beijing 100700, Peoples R China

[2] Taian City Cent Hosp Shandong Prov, Dept Neonatol & NICU, Tai An, Shandong, Peoples R China

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2016年 / 29卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Adverse effects; interventions; intrauterine growth restriction; neurodevelopment; INDIVIDUALIZED DEVELOPMENTAL CARE; INDUCED CEREBRAL APOPTOSIS; FOR-GESTATIONAL-AGE; PRETERM INFANTS; FETAL RATS; COGNITIVE FUNCTION; ASSESSMENT PROGRAM; OXIDATIVE STRESS; YOUNG-ADULTS; RISK-FACTORS;

D O I：

10.3109/14767058.2015.1015417

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Intrauterine growth restriction (IUGR) is associated with higher rates of fetal, perinatal, and neonatal morbidity and mortality. The consequences of IUGR include short-term metabolic, hematological and thermal disturbances that lead to metabolic syndrome in children and adults. Additionally, IUGR severely affects short- and long-term fetal brain development and brain function (including motor, cognitive and executive function) and neurobehavior, especially neuropsychology. This review details the adverse effects of IUGR on fetal brain development and discusses intervention strategies.

引用

页码：660 / 668

页数：9

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