Effects of non-thermal plasma on the electrical properties of an erythrocyte membrane

被引:6
|
作者
Lee, Jin Young [1 ]
Baik, Ku Youn [1 ]
Kim, Tae Soo [1 ]
Lim, Jaekwan [2 ]
Uhm, Han S. [1 ]
Choi, Eun Ha [1 ]
机构
[1] Kwangwoon Univ, Dept Elect & Biol Phys, Seoul 139701, South Korea
[2] Korea Univ, Coll Med, Artificial Organ Res Ctr, Seoul 136705, South Korea
基金
新加坡国家研究基金会;
关键词
LIPID-PEROXIDATION; OXIDATIVE STRESS; CELLS; PHOSPHOLIPIDS; CHARGE;
D O I
10.1063/1.4930872
中图分类号
O59 [应用物理学];
学科分类号
摘要
Non-thermal plasma is used here for membrane oxidation and permeabilization in which the electrical properties of an erythrocyte membrane are investigated after treatments. The zeta potential as measured by electrophoresis shows the increased negativity of the membrane surface potential (psi(s)). The secondary electron emission coefficient (gamma) measured by a focused ion beam shows a decrease in the dipole potential (psi(d)) of lipid molecules. The voltage-sensitive fluorescent intensity as measured by flow cytometry shows a decrease in the trans-membrane potential (Delta psi) through the lipid bilayer membrane. These results allow us to take a step forward to unveil the complex events occurring in plasma-treated cells. (C) 2015 AIP Publishing LLC.
引用
收藏
页数:5
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