Dienogest. A possible conservative approach in bladder endometriosis. Results of a pilot study

被引：39

作者：

Angioni, Stefano ^{[1
]}

Nappi, Luigi ^{[2
]}

Pontis, Alessandro ^{[1
]}

Sedda, Federica ^{[1
]}

Luisi, Stefano ^{[3
]}

Mais, Valerio ^{[1
]}

Melis, Gian Benedetto ^{[1
]}

机构：

[1] Univ Cagliari, Dept Surg Sci, Div Obstet & Gynecol, I-09042 Monserrato, CA, Italy

[2] Univ Foggia, Inst Obstet & Gynaecol, Dept Med & Surg Sci, Foggia, Italy

[3] Univ Siena, Dept Mol & Dev Med, Obstet & Gynecol, I-53100 Siena, Italy

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 2015年 / 31卷 / 05期

关键词：

Deep endometriosis; dienogest; dysuria; pelvic pain; DEEP ENDOMETRIOSIS; SURGICAL-TREATMENT; WOMEN; HYSTEROSCOPY; PREGNANCY; SYMPTOMS; EFFICACY; SURGERY; ACETATE; PAIN;

D O I：

10.3109/09513590.2015.1006617

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Deep endometriosis involvement of the bladder is uncommon but it is symptomatic in most of the cases. Although laparoscopic excision is very effective, some patients with no pregnancy desire require a medical approach. We performed a pilot study on the effect of a new progestin dienogest on bladder endometriosis. Six patients were treated for 12 months with dienogest 2 mg/daily. Pain, urinary symptoms, quality of life, nodule volume and side effects were recorded. During treatment, symptoms improved very quickly and the nodules exhibit a remarkable reduction in size. Dienogest may be an alternative approach to bladder endometriosis.

引用

页码：406 / 408

页数：3

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