Short Report: Molecular Detection of HPV and Chlamydia trachomatis Infections in Brazilian Women with Abnormal Cervical Cytology

被引：16

作者：

de Abreu, Andre L. P. ^{[1
]}

Nogara, Paula R. B. ^{[1
]}

Souza, Raquel P. ^{[1
]}

da Silva, Mariana C. ^{[1
]}

Uchimura, Nelson S. ^{[2
]}

Zanko, Rodrigo L. ^{[2
]}

Ferreira, Erika C. ^{[4
]}

Tognim, Maria C. B. ^{[3
]}

Teixeira, Jorge J. V. ^{[1
]}

Gimenes, Fabricia ^{[1
]}

Consolaro, Marcia E. L. ^{[1
]}

机构：

[1] Univ Estadual Maringa, Dept Anal Clin & Biomed, BR-87020900 Maringa, Parana, Brazil

[2] Univ Estadual Maringa, Dept Med, BR-87020900 Maringa, Parana, Brazil

[3] Univ Estadual Maringa, Dept Basic Sci Hlth, BR-87020900 Maringa, Parana, Brazil

[4] Univ Estadual Maringa, Programa Posgrad Ciencias Saude, BR-87020900 Maringa, Parana, Brazil

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2012年 / 87卷 / 06期

关键词：

RISK;

D O I：

10.4269/ajtmh.2012.12-0287

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The question of whether Chlamydia trachomatis (Ct) is a cofactor for human Papillomavirus (HPV) in cervical carcinogenesis is still controversial. We conducted a molecular detection study of both infections in 622 Brazilian women, including 252 women with different grades of abnormal cervical cytology and cervical cancer (CC; cases) and 370 women with normal cytology (controls). Although Ct infection did not seem related to CC carcinogenicity, women with abnormal cytology had a significant high rate of Ct infection. Therefore, it is important to adopt protocols for diagnosis and treatment of this bacterium in conjunction with screening for CC in this population.

引用

页码：1149 / 1151

页数：3