The Effects of Cadmium on Enzymatic Antioxidant System and Lipid Peroxidation of Human Erythrocytes in vitro and the Protective Role of Plasma Level of Vitamins C and E

被引：0
作者：
Tezcan, Ozlem [1 ]
Pandir, Dilek [1 ]
Bas, Hatice [1 ]
机构：
[1] Bozok Univ, Fac Arts & Sci, Dept Biol, TR-66100 Divanliyolu Yozgat, Turkey
来源：
POLISH JOURNAL OF ENVIRONMENTAL STUDIES | 2012年 / 21卷 / 06期
关键词：
antioxidant enzymes; cadmium; vitamins C and E; erythrocytes; in vitro; INDUCED OXIDATIVE STRESS; DNA-DAMAGE; INDUCED APOPTOSIS; DEFENSE SYSTEM; ASCORBIC-ACID; INDUCTION; SELENIUM; BLOOD; METAL; RATS;
D O I：
暂无
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
In our study, the effect of simultaneous pretreatment with plasma levels of vitamins C and E on the toxicity of CdCl2 in human erythrocytes was evaluated. We aimed to examine how several different doses of CdCl2 or CdCl2, in combination with vitamins, affects lipid peroxidation and the antioxidant defense system in vitro. Levels of malondialdehyde and the activities of antioxidant enzymes changed in CdCl2-treated groups in different concentrations. Vitamin-pretreated erythrocytes showed significant protection aganist the cytotoxic effects induced by low and moderate CdCl2 concentrations on the studied parameters.
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页码：1849 / 1854
页数：6
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