pH-Mediated Single Molecule Conductance of Cucurbit[7]uril

被引：7
作者：
Ai, Qiushuang [1 ]
Fu, Qiang [2 ]
Liang, Feng [1 ]
机构：
[1] Wuhan Univ Sci & Technol, State Key Lab Refractories & Met, Sch Chem & Chem Engn, Wuhan, Peoples R China
[2] Jiangxi Coll Tradit Chinese Med, Fuzhou, Peoples R China
来源：
FRONTIERS IN CHEMISTRY | 2020年 / 8卷
基金：
中国国家自然科学基金;
关键词：
recognition tunneling; single molecule conductance; pH-response; cucurbit[7]uril; melphalan; host-guest interactions; HOST-GUEST INTERACTIONS; MELPHALAN; ENCAPSULATION;
D O I：
10.3389/fchem.2020.00736
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Recognition tunneling technique owns the capability for investigating and characterizing molecules at single molecule level. Here, we investigated the conductance value of cucurbit[7]uril (CB[7]) and melphalan@CB[7] (Mel@CB[7]) complex molecular junctions by using recognition tunneling technique. The conductances of CB[7] and Mel@CB[7] with different pH values were studied in aqueous media as well as organic solvent. Both pH value and guest molecule have an impact on the conductance of CB[7] molecular junction. The conductances of CB[7] and Mel@CB[7] both showed slightly difference on the conductance under different measurement systems. This work extends the molecular conductance measurement to aqueous media and provides new insights of pH-responsive host-guest system for single molecule detection through electrical measurements.
引用
收藏
页数：8
相关论文
共 38 条
  • [1] A general and efficient method to form self-assembled cucurbit[n]uril monolayers on gold surfacest
    An, Qi
    Li, Guangtao
    Tao, Chengan
    Li, Yan
    Wu, Yiguang
    Zhang, Weixia
    [J]. CHEMICAL COMMUNICATIONS, 2008, (17) : 1989 - 1991
  • [2] pH-responsive supramolecular nanovalves based on cucurbit[6]uril pseudorotaxanes
    Angelos, Sarah
    Yang, Ying-Wei
    Patel, Kaushik
    Stoddart, J. Fraser
    Zink, Jeffrey I.
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2008, 47 (12) : 2222 - 2226
  • [3] Integrating Stimuli-Responsive Properties in Host-Guest Supramolecular Drug Delivery Systems
    Braegelman, Adam S.
    Webber, Matthew J.
    [J]. THERANOSTICS, 2019, 9 (11): : 3017 - 3040
  • [4] Stimuli-Responsive Polymers and Their Applications in Nanomedicine
    Cabane, Etienne
    Zhang, Xiaoyan
    Langowska, Karolina
    Palivan, Cornelia G.
    Meier, Wolfgang
    [J]. BIOINTERPHASES, 2012, 7 (1-4) : 1 - 27
  • [5] Hybrid Molecular-Junction Mapping Technique for Simultaneous Measurements of Single-Molecule Electronic Conductance and Its Corresponding Binding Geometry in a Tunneling Junction
    Chen, Haijian
    Li, Yunchuan
    Chang, Shuai
    [J]. ANALYTICAL CHEMISTRY, 2020, 92 (09) : 6423 - 6429
  • [6] pH-Responsive supramolecular DOX-dimer based on cucurbit[8]uril for selective drug release
    Cheng, Qian
    Li, Shengke
    Ma, Yanlong
    Yin, Hang
    Wang, Ruibing
    [J]. CHINESE CHEMICAL LETTERS, 2020, 31 (05) : 1235 - 1238
  • [7] The Long History of Molecular Electronics: Microelectronics Origins of Nanotechnology
    Choi, Hyungsub
    Mody, Cyrus C. M.
    [J]. SOCIAL STUDIES OF SCIENCE, 2009, 39 (01) : 11 - 50
  • [8] Reproducible measurement of single-molecule conductivity
    Cui, XD
    Primak, A
    Zarate, X
    Tomfohr, J
    Sankey, OF
    Moore, AL
    Moore, TA
    Gust, D
    Harris, G
    Lindsay, SM
    [J]. SCIENCE, 2001, 294 (5542) : 571 - 574
  • [9] Measurement of the conductance of single conjugated molecules
    Dadosh, T
    Gordin, Y
    Krahne, R
    Khivrich, I
    Mahalu, D
    Frydman, V
    Sperling, J
    Yacoby, A
    Bar-Joseph, I
    [J]. NATURE, 2005, 436 (7051) : 677 - 680
  • [10] Controlling factors in the synthesis of cucurbituril and its homologues
    Day, A
    Arnold, AP
    Blanch, RJ
    Snushall, B
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (24) : 8094 - 8100
1234