Case report: Coxiella burnetii vascular infection and lymphoma in the Netherlands

被引:9
作者
van Roeden, Sonja E. [1 ]
Melenotte, Clea [2 ]
Hermans, Mirjam H. A. [3 ]
Sinnige, Harm A. M. [4 ]
Nooijen, Peet T. G. A. [5 ]
Audoly, Gilles [2 ]
Hoepelman, Andy I. M. [1 ]
Oosterheert, Jan Jelrik [1 ]
Raoult, Didier [2 ]
Wever, Peter C. [3 ]
机构
[1] Univ Med Ctr Utrecht, Dept Internal Med & Infect Dis, Heidelberglaan 100, NL-3584 CX Utrecht, Netherlands
[2] Aix Marseille Univ, Mediterranee Infect, CNRS, IRD,INSERM,AP HM,URMITE,IHU, 19-21 Blvd Jean Moulin, F-13385 Marseille 05, France
[3] Jeroen Bosch Hosp, Dept Med Microbiol & Infect Control, Henri Dunantstr 1, NL-5223 GZ Shertogenbosch, Netherlands
[4] Jeroen Bosch Hosp, Dept Internal Med, Henri Dunantstr 1, NL-5223 GZ Shertogenbosch, Netherlands
[5] Jeroen Bosch Hosp, Dept Pathol, Henri Dunantstr 1, NL-5223 GZ Shertogenbosch, Netherlands
关键词
Coxiella burnetii; Q fever; Non-Hodgkin lymphoma; NON-HODGKIN-LYMPHOMA; Q-FEVER; ENDOCARDITIS; DIAGNOSIS; CRITERIA;
D O I
10.1007/s15010-017-1061-9
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Non-Hodgkin lymphoma has been linked to infection with Coxiella burnetii, potentially through overproduction of IL-10 during infection with C. burnetii. Description of a case report. We describe a patient with retroperitoneal non-Hodgkin lymphoma and vascular infection with C. burnetii. Immunofluorescence staining and fluorescence in situ hybridization targeting specific C. burnetii 16S rRNA were performed on the retroperitoneal lymphoma tissue sample obtained at diagnosis of NHL. Both were strongly positive for the presence of C. burnetii. This case provokes questions regarding a potential association between C. burnetii and NHL, and underlines the importance of further exploration of this association.
引用
收藏
页码:131 / 134
页数:4
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