A theoretical analysis of the Ti(IV)-catalyzed glycoaminocyanation reaction

被引：0
作者：
Soriano, Elena [1 ]
Marco-Contelles, Jose [2 ]
Ducatel, Helene [3 ]
Nguyen Van Nhien, Albert [3 ]
Postel, Denis [3 ]
机构：
[1] CSIC, Inst Invest Biomed, Lab Resonancia Magnet, E-28029 Madrid, Spain
[2] CSIC, Lab Radicales Libres, E-28006 Madrid, Spain
[3] Univ Picardie, Lab Glucides, UMR 6219, F-80039 Amiens, France
来源：
CARBOHYDRATE RESEARCH | 2008年 / 343卷 / 10-11期
关键词：
stereoselective reactions; titanium; Lewis acid; DFT methodology;
D O I：
10.1016/j.carres.2008.03.016
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The chelation of the Lewis acid Ti(OiPr)(4) provides the necessary conformational control to induce pi-facial selectivity on the cyanation process. The steric hindrance imposed by the alpha-substituent restrains the addition for L-amino acid derivatives. (c) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1835 / 1839
页数：5
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