Old chemotherapy makes a comeback: dual alkylator therapy for pediatric high-grade glioma

被引：5

作者：

Bouffet, Eric ^{[1
]}

Ramaswamy, Vijay ^{[1
]}

机构：

[1] Univ Toronto, Hosp Sick Children, Div Haematol Oncol, Toronto, ON, Canada

来源：

NEURO-ONCOLOGY | 2016年 / 18卷 / 10期

关键词：

TEMOZOLOMIDE; RADIOTHERAPY; LOMUSTINE; GLIOBLASTOMA; CHILDREN; TRIAL; ASTROCYTOMA; SURVIVAL; BRAIN;

D O I：

10.1093/neuonc/now200

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1333 / 1334

页数：2

共 13 条

[1] Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients [J].

Agnihotri, Sameer ;

Gajadhar, Aaron S. ;

Ternamian, Christian ;

Gorlia, Thierry ;

Diefes, Kristin L. ;

Mischel, Paul S. ;

Kelly, Joanna ;

McGown, Gail ;

Thorncroft, Mary ;

Carlson, Brett L. ;

Sarkaria, Jann N. ;

Margison, Geoffrey P. ;

Aldape, Kenneth ;

Hawkins, Cynthia ;

Hegi, Monika ;

Guha, Abhijit .

JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (01) :253-266

[2] Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group [J].

Cohen, Kenneth J. ;

Pollack, Ian F. ;

Zhou, Tianni ;

Buxton, Allen ;

Holmes, Emiko J. ;

Burger, Peter C. ;

Brat, Daniel J. ;

Rosenblum, Marc K. ;

Hamilton, Ronald L. ;

Lavey, Robert S. ;

Heideman, Richard L. .

NEURO-ONCOLOGY, 2011, 13 (03) :317-323

[3] RANDOMIZED PHASE-III TRIAL IN CHILDHOOD HIGH-GRADE ASTROCYTOMA COMPARING VINCRISTINE, LOMUSTINE, AND PREDNISONE WITH THE 8-DRUGS-IN-1-DAY REGIMEN [J].

FINLAY, JL ;

BOYETT, JM ;

YATES, AJ ;

WISOFF, JH ;

MILSTEIN, JM ;

GEYER, JR ;

BERTOLONE, SJ ;

MCGUIRE, P ;

CHERLOW, JM ;

TEFFT, M ;

TURSKI, PA ;

WARA, WM ;

EDWARDS, M ;

SUTTON, LN ;

BERGER, MS ;

EPSTEIN, F ;

AYERS, G ;

ALLEN, JC ;

PACKER, RJ .

JOURNAL OF CLINICAL ONCOLOGY, 1995, 13 (01) :112-123

[4] Long-Term Survival of Patients With Glioblastoma Treated With Radiotherapy and Lomustine Plus Temozolomide [J].

Glas, Martin ;

Happold, Caroline ;

Rieger, Johannes ;

Wiewrodt, Dorothee ;

Baehr, Oliver ;

Steinbach, Joachim P. ;

Wick, Wolfgang ;

Kortmann, Rolf-Dieter ;

Reifenberger, Guido ;

Weller, Michael ;

Herrlinger, Ulrich .

JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (08) :1257-1261

[5]

Grill J, 2016, NEURO-ONCOLOGY, V18, P77

[6] Phase II trial of lomustine plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03 [J].

Herrlinger, Ulrich ;

Rieger, Johannes ;

Koch, Dorothee ;

Loeser, Simon ;

Blaschke, Britta ;

Kortmann, Rolf-Dieter ;

Steinbach, Joachim P. ;

Hundsberger, Thomas ;

Wick, Wolfgang ;

Meyermann, Richard ;

Tan, Ta-Chih ;

Sommer, Clemens ;

Bamberg, Michael ;

Reifenberger, Guido ;

Weller, Michael .

JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (27) :4412-4417

[7] Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study [J].

Jakacki, Regina I. ;

Cohen, Kenneth J. ;

Buxton, Allen ;

Krailo, Mark D. ;

Burger, Peter C. ;

Rosenblum, Marc K. ;

Brat, Daniel J. ;

Hamilton, Ronald L. ;

Eckel, Sandrah P. ;

Zhou, Tianni ;

Lavey, Robert S. ;

Pollack, Ian F. .

NEURO-ONCOLOGY, 2016, 18 (10) :1442-1450

[8]

Jones C., 2016, NEUROONCOL

[9]

Ostrom QT, 2014, NEURO-ONCOLOGY, V16, P1, DOI [10.1093/neuonc/nov189, 10.1093/neuonc/nou223, 10.1093/neuonc/nou327, 10.1093/neuonc/nox158]

[10]

PLOWMAN J, 1994, CANCER RES, V54, P3793

← 1 2 →