The neuroprotective role of erythropoietin in the management of acute ischaemic stroke: from bench to bedside

被引：6
作者：
Ntaios, G. [1 ]
Savopoulos, C. [1 ]
Chatzinikolaou, A. [1 ]
Hatzitolios, A. I. [1 ]
机构：
[1] Aristotle Univ Thessaloniki, AHEPA Hosp, Propedeut Dept Internal Med 1, Thessaloniki 54636, Greece
来源：
ACTA NEUROLOGICA SCANDINAVICA | 2008年 / 118卷 / 06期
关键词：
erythropoietin; stroke; neuroprotection; carbamylated erythropoietin; asialic erythropoietin;
D O I：
10.1111/j.1600-0404.2008.01039.x
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Recombinant human erythropoietin was produced soon after the discovery of the erythropoietin gene in 1985 and since then, it is used in various clinical conditions such as chronic renal failure. Moreover, experimental studies have shown that erythropoietin exerts neuroprotective action as well. Recently, a clinical trial yielded promising results concerning the use of erythropoietin in stroke management. In this review, we summarize the main data which suggest that recombinant human erythropoietin and its analogues may indeed have a role in stroke treatment.
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收藏
页码：362 / 366
页数：5
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