Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium

被引：68

作者：

Choi, Youngwoon ^{[1
,2
]}

Hillman, Timothy R. ^{[1
]}

Choi, Wonjun ^{[2
]}

Lue, Niyom ^{[1
]}

Dasari, Ramachandra R. ^{[1
]}

So, Peter T. C. ^{[1
,3
]}

Choi, Wonshik ^{[2
]}

Yaqoob, Zahid ^{[1
]}

机构：

[1] MIT, George R Harrison Spect Lab, Laser Biomed Res Ctr, Cambridge, MA 02139 USA

[2] Korea Univ, Dept Phys, Seoul 136701, South Korea

[3] MIT, Dept Mech & Biol Engn, Cambridge, MA 02139 USA

来源：

PHYSICAL REVIEW LETTERS | 2013年 / 111卷 / 24期

基金：

新加坡国家研究基金会; 美国国家卫生研究院;

关键词：

MICROSCOPY;

D O I：

10.1103/PhysRevLett.111.243901

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-gated detection. From this matrix, we derive and experimentally implement an incident wave pattern that optimizes the detected signal corresponding to a specific arrival time. This leads to enhanced light delivery at the target depth. The proposed method will lay a foundation for efficient phototherapy and deep-tissue in vivo imaging in the near future.

引用

页数：5