Novel ent-kaurane dimers from Isodon rubescens var. rubescens

被引：32

作者：

Han, QB

Lu, Y

Zhang, LL

Zheng, QT

Sun, HD ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 13期

关键词：

ent-kaurane dimer; xindongnins M-O; Isodon rubescens var. rubescens;

D O I：

10.1016/j.tetlet.2004.02.051

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three novel asymmetric ent-kaurane dimers xindongnins M-O (1-3) were isolated from Isodon rubescens var. rubescens. Their structures were elucidated by spectroscopic methods including 2D NMR analysis. The relative stereochemistry of 1 was determined by single crystal X-ray diffraction which also confirmed the unique linkage of a single carbon-carbon bond between the two subunits of this dimer. A biogenetic pathway was proposed for the formation of these dimers. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2833 / 2837

页数：5

共 10 条

[1] Two novel ent-kaurene diterpenoids from Isodon rubescens [J].

Han, QB ;

Jiang, B ;

Zhang, JX ;

Niu, XM ;

Sun, HD .

HELVETICA CHIMICA ACTA, 2003, 86 (03) :773-777

[2]

Han QB, 2003, HETEROCYCLES, V60, P933

[3]

Han QB, 2003, ACTA CHIM SINICA, V61, P1077

[4]

Han QB, 2003, CHEM PHARM BULL, V51, P790, DOI 10.1248/cpb.51.790

[5] Cytotoxic constituents of Isodon rubescens var. lushiensis [J].

Han, QB ;

Zhao, AH ;

Zhang, JX ;

Lu, Y ;

Zhang, LL ;

Zheng, QT ;

Sun, HD .

JOURNAL OF NATURAL PRODUCTS, 2003, 66 (10) :1391-1394

[6]

Han QB, 2003, CHINESE J ORG CHEM, V23, P270

[7]

LU Y, 1992, CHINESE CHEM LETT, V3, P637

[8]

Na Z, 2002, CHINESE J CHEM, V20, P884

[9]

SUN HD, 1985, ACTA CHIM SINICA, V2, P127

[10]

ZHAO Q-Z, 1991, Acta Botanica Yunnanica, V13, P205

← 1 →