Flow-injection biamperometric determination of epinephrine

被引：0

作者：

Mateo, JVG

Kojlo, A

机构：

[1] WARSAW UNIV BRANCH,INST CHEM,PL-15443 BIALYSTOK,POLAND

[2] UNIV POLITECN VALENCIA,DEPT QUIM,E-46071 VALENCIA,SPAIN

[3] COLEGIO UNIV CEU,DEPT QUIM,VALENCIA,SPAIN

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 1997年 / 15卷 / 12期

关键词：

biamperometry; flow injection; catecholamines; epinephrine; adrenaline;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A flow-injection manifold is proposed for the determination of epinephrine. The experimental procedure is based on the indirect biamperometric detection of the drug by using Fe(III)-Fe(II) as an indicating redox system and a flow-through detector with two polarized Pt wire electrodes. The calibration graph is linear over the range 0.3-20 mu g ml(-1) of epinephrine. The relative standard deviation for the determination of 10 mu g ml(-1) of epinephrine is 1.5% (n = 25) and the sample throughput is 153 h(-1). The method was applied to the determination of epinephrine in two commercially available pharmaceutical preparations. (C) 1997 Elsevier Science B.V.

引用

页码：1821 / 1828

页数：8

共 21 条

[1] TITRIMETRIC DETERMINATION OF CATECHOLAMINES AND RELATED-COMPOUNDS VIA BROMINE OXIDATION AND SUBSTITUTION [J].