A guided bone regeneration membrane composed of hydroxyapatite and polyurethane

被引：0

作者：

Dong, Zhi-Hong ^{[1
]}

Zhang, Li ^{[1
]}

Li, Yu-Bao ^{[1
]}

Zhou, Gang ^{[1
]}

Lee, Soo-Whon

机构：

[1] Sichuan Univ, Analyt & Testing Ctr, Res Ctr Nanobiomat, Chengdu 610064, Peoples R China

来源：

JOURNAL OF CERAMIC PROCESSING RESEARCH | 2008年 / 9卷 / 05期

关键词：

Hydroxyapatite; Polyurethane; Composite membrane; Characterization; Biocompatiblity;

D O I：

暂无

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

A hydroxyapatite (HA,10 wt%) and polyurethane (PU) composite as a guided bone regeneration (GBR)membrane was obtained from the polycondensation or polyaddition of diisocyanates and hydroxyl groups by a solvent evaporation method. The structure and properties of the membrane were investigated by XRD, IR, SEM, water absorption, wettability and a cell culture test in vitro. The results show that hydroxyapatite particles were dispersed uniformly in the polyurethane matrix and interfacial bonding between hydroxyapatite and polyurethane was formed. The hydroxyapatite/polyurethane membrane has good hydrophilicity and the surface pores can promote cell adhesion and growth. MTT (3-{4,5-dimethylthiazol-2yl}-2,5-diphenyl-2H-tetrazolium bromide) assay and light microscopy observation indicate that the hydroxyapatite/polyurethane membrane demonstrates excellent biocompatibility. The hydroxyapatite/polyurethane membrane will hopefully be selected as a guided bone regeneration and tissue engineering.

引用

页码：478 / 481

页数：4

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