Autophagy and oral cancers: A short review

被引：8

作者：

Chowdhury, R. M. ^{[1
]}

Singh, G. ^{[1
]}

Joshi, A. ^{[2
]}

Singh, D. K. ^{[1
]}

Bhatia, S. ^{[1
]}

Goswami, S. ^{[1
]}

机构：

[1] Vyas Dent Coll & Hosp, Dept Oral & Maxillofacial Pathol, Pali Rd, Jodhpur 342005, Rajasthan, India

[2] Joshi Dent Clin, Eidgah Rd, Jodhpur 342001, Rajasthan, India

来源：

JOURNAL OF STOMATOLOGY ORAL AND MAXILLOFACIAL SURGERY | 2018年 / 119卷 / 01期

关键词：

Autophagy; Oral Cancer; Treatment; ONCOPROTEIN; HEAD;

D O I：

10.1016/j.jormas.2017.11.001

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Autophagy is a catabolic process, which involves recycling of cellular elements and it seems to play a major role in etiopathogenesis of cancers. Autophagy is thought to buffer metabolic stress, thereby aiding in cell survival. Also, it is found that inhibiting autophagy under deficient nutrition can restore cell death to apoptosis. Therefore, autophagy plays a dual role in cancer therapeutics. Globally oral cancer is a major concern of numerous deaths, so comprehensive work needs to be undertaken in the field of its progression and to determine positive treatment modalities. There exists a serious dearth of knowledge to understand and comprehend the process of autophagy, and it is beyond doubt that further research in this field would bring forth several new methods of cancer prevention and treatment. (C) 2017 Elsevier Masson SAS. All rights reserved.

引用

页码：37 / 39

页数：3

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