Five New Cycloartane-Type Triterpenoid Saponins from Nervilia fordii

被引:8
作者
Wei, Liu-Bin [1 ]
Yuan, Hong-E [1 ]
Chen, Jin-Man [1 ]
Wang, Qing-Qing [1 ]
Wang, Hui [2 ]
Ye, Wen-Cai [1 ]
Zhou, Guang-Xiong [1 ]
机构
[1] Jinan Univ, Guangdong Prov Key Lab Pharmacodynam Constituents, Inst Tradit Chinese Med & Nat Prod, Coll Pharm, Guangzhou 510632, Guangdong, Peoples R China
[2] Jinan Univ, Sch Med, Guangzhou 510632, Guangdong, Peoples R China
关键词
Nervilia fordii; Cycloartane glycosides; Cytotoxic activity; Nervisides D?-?H; Glycosides; GLYCOSIDES;
D O I
10.1002/hlca.201200139
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Five new cycloartane glycosides, nervisides DH (15), were isolated from the AcOEt- and H2O-soluble portions of the 90% EtOH extract of the aerial part of the plant Nervilia fordii. The structures of the isolated glycosides were elucidated by extensive spectroscopic analysis including HR-ESI-MS and NMR data. The isolated nervisides DH were evaluated for the cytotoxic activity in vitro against human-tumor cell lines (CNE, Hep-2 and HepG2) with the MTT method.
引用
收藏
页码:150 / 157
页数:8
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