Therapeutic Effects of Quercetin on Inflammation, Obesity, and Type 2 Diabetes

被引:151
作者
Chen, Shuang [1 ]
Jiang, Hongmei [1 ]
Wu, Xiaosong [1 ]
Fang, Jun [1 ,2 ,3 ]
机构
[1] Hunan Agr Univ, Coll Anim Sci & Technol, Coll Biosci & Biotechnol, Changsha 410128, Hunan, Peoples R China
[2] Hunan Agr Univ, Hunan Prov Univ Key Lab Agr Biochem & Biotransfor, Changsha 410128, Hunan, Peoples R China
[3] Hunan CoInnovat Ctr Ultilizat Bot Funct Ingredien, Changsha 410128, Hunan, Peoples R China
基金
中国国家自然科学基金;
关键词
NATURALLY-OCCURRING FLAVONOIDS; NF-KAPPA-B; ABDOMINAL ADIPOSITY; TNF-ALPHA; INHIBITION; AP-1;
D O I
10.1155/2016/9340637
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
In previous studies, abdominal obesity has been related to total low-grade inflammation and in some cases has resulted in insulin resistance and other metabolism related disorders such as diabetes. Quercetin is a polyphenol, which is a derivative of plants, and has been shown in vitro as well as in a few animal models to have several potential anti-inflammatory as well as anticarcinogenic applications. The substance has also been shown to aid in the attenuation of lipid peroxidation, platelet aggregation, and capillary permeability. However, further research is called for to gain a better understanding of how quercetin is able to provide these beneficial effects. This manuscript reviewed quercetin's anti-inflammatory properties in relation to obesity and type 2 diabetes.
引用
收藏
页数:5
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