Rotaxanes of cyclic peptides

被引：40
作者：
Aucagne, V [1 ]
Leigh, DA [1 ]
Lock, JS [1 ]
Thomson, AR [1 ]
机构：
[1] Univ Edinburgh, Sch Chem, Edinburgh EH9 3JJ, Midlothian, Scotland
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 06期
关键词：
D O I：
10.1021/ja057206q
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of rotaxanes derived from the synthetic peptide macrocycles cyclo(l-ProGly)4 and cyclo(l-ProGly)5 and diammonium threads is described. [2]Rotaxanes are formed in good yields (56-63%), despite the disruption of internal amide-amide hydrogen bonding in the macrocycles. Copyright © 2006 American Chemical Society.
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页码：1784 / 1785
页数：2
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