Recombinant beta-glucanase production and plasmid stability of Bacillus subtilis in cyclic fed batch culture

被引：6

作者：

Argyropoulos, D ^{[1
]}

Lynch, HC ^{[1
]}

机构：

[1] DEPT FOOD SCI & TECHNOL,BIOTECHNOL & BIOCHEM ENGN LABS,READING RG6 6AP,BERKS,ENGLAND

来源：

BIOTECHNOLOGY TECHNIQUES | 1997年 / 11卷 / 03期

关键词：

D O I：

10.1023/A:1018409715438

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Recombinant beta-glucanase production and plasmid stability were higher in cyclic fed batch culture than in batch and chemostat culture. Plasmid stability was maintained indefinitely in cyclic fed batch cultures of Bacillus subtilis when subjected to cycle periods of 2 or 4 hours. Cycle periods greater than 6 hours resulted in loss of the plasmid. In batch and chemostat cultures plasmid loss was rapid. beta-1,3-glucanase productivity was highest in cyclic fed batch culture.

引用

页码：187 / 190

页数：4

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