Total cost-effectiveness of mammography screening strategies

被引：0

作者：

Mittmann, Nicole ^{[1
,2
]}

Stout, Natasha K. ^{[3
,4
]}

Lee, Pablo ^{[5
]}

Tosteson, Anna N. A. ^{[6
]}

Trentham-Dietz, Amy ^{[7
,8
]}

Alagoz, Oguzhan ^{[7
,8
,9
]}

Yaffe, Martin J. ^{[10
,11
,12
]}

机构：

[1] Sunnybrook Res Inst, Hlth Outcomes & PharmacoEcon HOPE Res Ctr, Toronto, ON, Canada

[2] Univ Toronto, Toronto, ON M5S 1A1, Canada

[3] Harvard Med Sch, Dept Populat Med, Boston, MA USA

[4] Harvard Pilgrim Hlth Care Inst, Boston, MA USA

[5] Massachusetts Gen Hosp, Inst Technol Assessment, Boston, MA 02114 USA

[6] Geisel Sch Med Dartmouth, Dartmouth Inst Hlth Policy & Clin Practice, Hanover, NH USA

[7] Univ Wisconsin, Dept Populat Hlth Sci, Madison, WI 53706 USA

[8] Univ Wisconsin, Carbone Canc Ctr, Madison, WI 53706 USA

[9] Univ Wisconsin, Dept Ind & Syst Engn, Madison, WI 53706 USA

[10] Sunnybrook Res Inst, Phys Sci Program, Toronto, ON, Canada

[11] Univ Toronto, Dept Med Biophys, Toronto, ON M5S 1A1, Canada

[12] Univ Toronto, Dept Med Imaging, Toronto, ON M5S 1A1, Canada

来源：

HEALTH REPORTS | 2015年 / 26卷 / 12期

基金：

美国国家卫生研究院;

关键词：

Breast screening; economic analysis; microsimulation model; preventive health; BREAST-CANCER; IMPACT; WOMEN; US; GUIDELINES; SERVICES; AGE;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Breast cancer screening technology and treatment have improved over the past decade. This analysis evaluates the total cost-effectiveness of various breast cancer screening strategies in Canada. Data and methods: Using the Wisconsin Cancer Intervention and Surveillance Monitoring Network (CISNET) breast cancer simulation model adapted to the Canadian context, costs and quality-adjusted life years (QALY) were evaluated for 11 mammography screening strategies that varied by start/stop age and screening frequency for the general population. Incremental cost-effectiveness ratios are presented, and sensitivity analyses are used to assess the robustness of model conclusions. Results: Incremental cost-effectiveness analysis showed that triennial screening at ages 50 to 69 was the most cost-effective at $94,762 per QALY. Biennial ($97,006 per QALY) and annual ($226,278 per QALY) strategies had higher incremental ratios. Interpretation: The benefits and costs of screening rise with the number of screens per woman. Decisions about screening strategies may be influenced by willingness to pay and the rate of recall for further examination after positive screens.

引用

页码：16 / 25

页数：10

共 42 条

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