Brownian motion in a harmonic trap: magnetic tweezers experiment and its simulation

被引：3
|
作者：
Ran Shi-Yong [1 ]
机构：
[1] Wenzhou Univ, Sch Phys & Elect Informat Engn, Wenzhou 325035, Peoples R China
来源：
ACTA PHYSICA SINICA | 2012年 / 61卷 / 17期
基金：
中国国家自然科学基金;
关键词：
Brownian motion; hamonic trap; magnetic tweezers; DNA; MOLECULE;
D O I：
10.7498/aps.61.170503
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
The Brownian motion in a harmonic trap is studied by magnetic tweezers experiment and computer simulation. The results of the experiment and simulation validate the theory. Then the theory is used to analyze the experimental results including the effect of persistent length of DNA on the displacement distribution of the bead and the error in force measurements. It can be concluded that the variation of the persistent length affects more the Brownian motion along the DNA chain than in the other direction; under a small force, a considerable error of the force measurement will occur.
引用
收藏
页数：7
相关论文
共 19 条
  • [1] Power spectrum analysis for optical tweezers
    Berg-Sorensen, K
    Flyvbjerg, H
    [J]. REVIEW OF SCIENTIFIC INSTRUMENTS, 2004, 75 (03) : 594 - 612
  • [2] Einstein A., 1956, INVESTIGATIONS THEOR, P1
  • [3] Hao Bai-Lin, 2011, Wuli, V40, P1
  • [4] Hinterdorfer P, 2009, HANDBOOK OF SINGLE-MOLECULE BIOPHYSICS, P1, DOI 10.1007/978-0-387-76497-9
  • [5] Trapping stiffness measurement with brownian motion analysis method at low sampling frequency
    Jiang, YQ
    Guo, HL
    Liu, CX
    Li, ZL
    Cheng, BY
    Zhang, DZ
    Jia, ST
    [J]. ACTA PHYSICA SINICA, 2004, 53 (06) : 1721 - 1726
  • [6] Assembly of single chromatin fibers depends on the tension in the DNA molecule: Magnetic tweezers study
    Leuba, SH
    Karymov, MA
    Tomschik, M
    Ramjit, R
    Smith, P
    Zlatanova, J
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (02) : 495 - 500
  • [7] Direct measurements of constrained Brownian motion of an isolated sphere between two walls
    Lin, BH
    Yu, J
    Rice, SA
    [J]. PHYSICAL REVIEW E, 2000, 62 (03): : 3909 - 3919
  • [8] Stretching DNA
    Marko, JF
    Siggia, ED
    [J]. MACROMOLECULES, 1995, 28 (26) : 8759 - 8770
  • [9] Ran Shi-Yong, 2007, Wuli, V36, P228
  • [10] Single molecule DNA compaction by purified histones
    Ran ShiYong
    Wang XiaoLing
    Fu WenBo
    Wang WeiChi
    Li Ming
    [J]. CHINESE SCIENCE BULLETIN, 2008, 53 (06): : 836 - 841
12