It should come as no surprise that membrane lipids can profoundly affect the functions of membrane proteins. In turn, lipid-protein interactions play a major role in normal cell functioning, and hence in human health and disease. This meeting on 'Lipid-Protein Interactions in Membranes' brought together researchers from around the world to a serene oasis within the bustling metropolis of Hyderabad, India. Major aspects of this emerging field where lipids and proteins intersect were covered, with a particular focus on membrane receptors, ion channels and transporters, as well as technical challenges and advances. Here, we summarize the presentations, highlighting their clinical implications.